203731-63-9Relevant academic research and scientific papers
Synthesis and face- and stereo-selective cycloadditions of α-alkoxy cyclic nitrones
Ali, Sk. Asrof,Hashmi, S. M. Azhar,Wazeer, Mohammed I. M.
, p. 1255 - 1256 (1998)
α-Alkoxy cyclic nitrones (5), stabilized by the presence of hydroquinone, underwent face-, regio- and stereo-selective cycloaddition reaction with normal alkenes to afford bicyclic isoxazolidines (8) efficiently.
Peracid induced ring opening of some isoxazolidines and oxidation of saturated 1,3-oxazines to new heterocyclic nitrones
Hashmi, Syed M. A.,Ali, Sk. Asrof,Wazeer, Mohammed I. M.
, p. 12959 - 12972 (1998)
The regiochemistry of peracid-induced ring opening of a number of isoxazolidines is investigated. The mechanism of the ring opening reaction and the effects of substituents on the regiochemical behavior have been discussed. The oxidation process gives an equilibrium mixture of nitrone and its six-membered ring hydroxylamine tautomer; the ratio of which is found to depend on the substituents. The tautomeric cyclic hydroxylamine has been convened to a new class of nitrones by oxidation with mercury (II) oxide or p-benzoquinone. One of the cyclic hydroxylamine lacking hydrogen at the α- carbons has been oxidized to nitroxide spin label.
