203739-35-9Relevant academic research and scientific papers
Asymmetric synthesis of ω-bromo-2(S)-methyl acids as precursors for novel arginine, lysine, and mercapto residues
Hadden, M. Kyle,Kokko, Kyle P.,Dix, Thomas A.
, p. 1675 - 1680 (2005)
A series of ω-bromo-2(S)-methyl acids has been synthesized as precursors of novel arginine (Arg), lysine (Lys), and mercapto analogues. These intermediates contain α-methyl groups and are designed to mask the N-terminal amine when incorporated in pharmaceutically relevant peptides. Copyright Taylor & Francis, Inc.
Asymmetric synthesis of ω-bromo-2(S)-azido acids as precursors for the synthesis of novel amino acids
Lundquist IV, Joseph T.,Dix, Thomas A.
, p. 775 - 778 (2007/10/03)
A series of ω-bromo-2(S)-azido acids with side-chain lengths ranging from 3-5 methylene units has been synthesized. These intermediates enable the facile synthesis of chiral non-natural amino acids containing virtually any nucleophile capable of substituting the ω-bromo group.
