203791-36-0Relevant articles and documents
Syntheses and GABA uptake properties of 6-ether- and 6-enol ether-substituted nipecotic acids
N'Goka, Victor,Bissantz, Caterina,Bisel, Philippe,Stenbol, Tine B.,Krogsgaard-Larsen, Povl,Schlewer, Gilbert
, p. 633 - 638 (2004)
6-Aralkylether- and 6-arylenol-ether-substituted nipecotic acids were synthesized. These analogues are poor GABA uptake inhibitors. The electronegative region concept developed in the N-substituted nipecotic acid series cannot be transferred on the side c
C- or O- alkylation of 5-ethoxycarbonyl-2-hydroxymethyl pyridine with arylmethane derivatives
Bissantz, Caterina,Bisel, Philippe,Schlewer, Gilbert
, p. 133 - 134 (1998)
According to the experimental conditions 5-ethoxycarbonyl-2-hydroxymethyl pyridine was C- or O- alkylated by arylmethane derivatives.