20387-71-7Relevant articles and documents
A Convenient Preparation of 4,8-Dimethoxy-3-substituted-2(1H)-quinolones by an Electrophilic Reaction through Base-induced Deprotonation and its Synthetic Application for the Synthesis of New Alkaloids, 3,4,8-Trimethoxy-2(1H)-quinolone and 3-Formyl-4,7,8-trimethoxy-2(1H)-quinolone(Glycocitridine)
Tagawa, Yoshinobu,Kawaoka, Takamitsu,Goto, Yoshinobu
, p. 1677 - 1683 (2007/10/03)
Some 4,8-dimethoxy-3-substituted-2(1H)-quinolones were prepared by electrophilic reaction of 4,8-dimethoxy-2(1H)-quinolone with electrophiles in the presence of n-butyllithium-N,N,N',N',-tetramethylethylenediamine in fairly good yields. This present method was successfully applied for the synthesis of two new alkaloids bearing the 4,8-dimethoxy-2(1H)-quinolone skeleton.