203932-97-2

Upstream product

• 88-21-1 2-amino-1-benzenesulfonic acid 
• 106-47-8 4-chloro-aniline 
• 63132-70-7 2-amino-N-(4-chlorophenyl) benzenesulfonamide 
• 1694-92-4 2-Nitrobenzenesulfonyl chloride 

Downstream Products

• 1394932-08-1 C₁₆H₁₃ClN₄O₂S 
• 1394932-07-0 C₁₅H₁₁ClN₄O₂S 
• 1448463-66-8 2-N-(4-chlorophenyl)-3-ethoxy-1,2,4-benzothiadiazine 1,1-dioxide 
• 1448463-68-0 ethyl 2-aminophenylsulfonyl-(4-chlorophenyl)carbamate 
• 1448463-63-5 ethyl 2-azidophenylsulfonyl-(4-chlorophenyl)carbamate 
• 1448463-65-7 C₃₃H₂₈ClN₂O₄PS 

Relevant academic research and scientific papers

Facile synthesis of benzothiadiazine 1,1-dioxides, a precursor of RSV inhibitors, by tandem amidation/ intramolecular aza-Wittig reaction

Reaction of o-azidobenzenesulfonamides with ethyl carbonochloridate afforded the corresponding amide derivatives, which gave 3-ethoxy-1,2,4- benzothiadiazine 1,1-dioxides through an intramolecular aza-Wittig reaction. The reaction was found to be general

Dibenzo[1,2,5]thiadiazepines are non-competitive GABAA receptor antagonists

A new process for obtaining dibenzo[c,f][1,2,5]thiadiazepines (DBTDs) and their effects on GABAA receptors of guinea pig myenteric neurons are described. Synthesis of DBTD derivatives began with two commercial aromatic compounds. An azide group was obtain

An one-pot approach to the synthesis of triazolobenzothiadiazepine 1,1-dioxide derivatives by basic alumina-supported azide-alkyne [3+2] cycloaddition

An efficient one-pot strategy for the synthesis of triazolobenzothiadiazepine 1,1-dioxide derivatives has been developed by the reaction of 2-azido-N-substituted benzenesulfonamides and propargyl bromide in basic alumina under microwave condition via [3+2] azide-alkyne cycloaddition reaction. This protocol has synthetic advantages in terms of low environmental impact and short reaction time.