204058-11-7Relevant academic research and scientific papers
Constrained phenylalanine derivatives by enyne metathesis and Diels-Alder reaction
Kotha, Sambasivarao,Sreenivasachary, Nampally,Brahmachary, Enugurthi
, p. 787 - 792 (2001)
A conceptually new approach for the synthesis of indane-based α-amino acid derivatives is reported. In this regard, the synthesis of five-membered exocyclic and five-membered inner-outer ring diene building blocks (7 and 15) containing α-amino acid moieties is described. Diene 15 is prepared by an enyne metathesis reaction as a key step. In this paper, a full account of our work regarding the Diels-Alder reaction of these dienes with various dienophiles, and the subsequent oxidation of the cycloadducts to give various indane-based α-amino acid derivatives is reported.
Synthesis of constrained α-amino acid derivatives via enyne metathesis reaction
Kotha, Sambasivarao,Sreenivasachary, Nampally,Brahmachary, Enugurthi
, p. 2805 - 2808 (2007/10/03)
Synthesis of a diene building block via enyne metathesis reaction and its usage in the preparation of constrained α-amino acid derivatives is described.
Synthesis of constrained α-amino acid derivatives via ring-closing olefin metathesis
Kotha, Sambasivarao,Sreenivasachary, Nampally
, p. 257 - 260 (2007/10/03)
Five and seven membered constrained α-amino acid derivatives were synthesized using ring-closing metathesis reaction as a key step.
