204078-35-3

Basic information

• Product Name: 3-(4-METHYLPIPERAZIN-1-YL)BENZONITRILE
• Synonyms: 3-(4-METHYLPIPERAZIN-1-YL)BENZONITRILE;3-(4-Methylpiperazine-1-yl)benzonitrile
• CAS NO: 204078-35-3
• Molecular Formula: C₁₂H₁₅N₃
• Molecular Weight: 201.27
• Product Categories: Boron, Nitrile, Thio,& TM-Cpds
• Mol File: 204078-35-3.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 340.2 °C at 760 mmHg
• Flash Point: 146.8 °C
• Appearance: /
• Density: 1.14 g/cm³
• Vapor Pressure: 8.76E-05mmHg at 25°C
• Refractive Index: 1.598
• CAS DataBase Reference: 3-(4-METHYLPIPERAZIN-1-YL)BENZONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-METHYLPIPERAZIN-1-YL)BENZONITRILE(204078-35-3)
• EPA Substance Registry System: 3-(4-METHYLPIPERAZIN-1-YL)BENZONITRILE(204078-35-3)

Safety Data

• Hazardous Substances Data: 204078-35-3(Hazardous Substances Data)

Usage

General Description

3-(4-Methylpiperazin-1-yl)benzonitrile is a chemical compound with the molecular formula C13H16N4. It is a white solid and is commonly used as a building block in the synthesis of pharmaceuticals and other organic compounds. This chemical contains a benzene ring with a nitrile group and a methylpiperazine side chain, making it useful for the development of various drugs and biologically active molecules. Its properties and reactivity allow for versatile applications in the field of medicinal chemistry and drug discovery, making it an important intermediate in the production of pharmaceuticals and related compounds.

InChI:InChI=1/C12H15N3/c1-14-5-7-15(8-6-14)12-4-2-3-11(9-12)10-13/h2-4,9H,5-8H2,1H3

Upstream product

• 109-01-3 1-methyl-piperazine 
• 403-54-3 m-Fluorobenzonitrile 

Downstream Products

• 672325-37-0 (3-(4-methylpiperazin-1-yl)phenyl)methanamine 

Relevant articles and documents

Azaindolylidene derivatives as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them

The present invention is directed to compounds of the formula or pharmaceutically acceptable salts, prodrug, solvate or optical isomer thereof, pharmaceutical compositions containing same and use thereof for treating diseases linked to disregulated cell p

HETEROCYCLIC AMIDES WITH ANTI-TUBERCULOSIS ACTIVITY

Compounds having the general structure (I) : wherein A is selected from the group consisting of oxygen, sulfur, and NR15, and R15 is selected from the group consisting of H, alkyl, aryl, substituted alkyl, and substituted aryl; B, D, and E are each independently selected from the group consisting of CH, nitrogen, sulfur and oxygen; R1 is selected from the group consisting of nitro, halo, alkyl ester, phenylsulfanyl, phenylsulfinyl, phenylsulfonyl and sulfonic acid; t is an integer from 1 to 3; and X is a substituted amide and methods of using the novel compounds for treating infections caused microorganisms, including Mycobacterium tuberculosis.

PYRAZOLO[1,5-A]PYRIMIDIN-7-YL-AMINE DERIVATIVES FOR USE IN THE TREATMENT OF PROTEIN KINASE DEPENDENT DISEASES

The invention relates to the use of pyrazolo[1,5a]pyrimidin-7-yl amine compounds and salts thereof in the treatment of kinase dependent diseases and for the manufacture of pharmaceutical preparations for the treatment of said diseases, novel pyrazolo[1,5a]pyrimidin-7-yl amine compounds, and a process for the preparation of the novel pyrazolo[1,5a]pyrimidin-7-yl amine compounds.