20410-95-1 Usage
General Description
6 alpha-naloxol, also known as 6α-naloxol, is a natural chemical compound that acts as an opioid antagonist. It is an active metabolite of the opioid drug naloxone, and it is also produced in small amounts in the human body as a metabolite of endogenous opioids. 6 alpha-naloxol works by binding to the same receptors in the brain as opioids, but it does not produce the same effects. It is thought to have potential therapeutic applications in the treatment of opioid addiction and overdose, as well as in the regulation of pain and stress responses in the body. Research on the effects and uses of 6 alpha-naloxol is ongoing, and it continues to be a subject of interest in the field of pharmacology and medicine.
Check Digit Verification of cas no
The CAS Registry Mumber 20410-95-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,4,1 and 0 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 20410-95:
(7*2)+(6*0)+(5*4)+(4*1)+(3*0)+(2*9)+(1*5)=61
61 % 10 = 1
So 20410-95-1 is a valid CAS Registry Number.
InChI:InChI=1/C19H23NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,13-14,17,21-23H,1,5-10H2/t13-,14+,17-,18-,19+/m0/s1
20410-95-1Relevant articles and documents
Ring C conformation of 6beta-naltrexol and 6alpha-naltrexol. Evidence from proton and carbon-13 nuclear magnetic resonance.
Brine,Praskash,Hart,Kotchmar,Moreland,Carroll
, p. 3445 - 3448 (1976)
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PROCESS FOR MAKING MORPHINAN-6alpha-OLS
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Page/Page column 7, (2010/03/02)
The present invention provides a process whereby morphinan-6-ones can be converted stereospecifically to the corresponding morphinan-6α-ols by catalytic hydrogenation under basic conditions.
Morphine Alkaloids, Part 114 A. Stereohomogeneous Synthesis of N-Demethyl-N-Substituted-14-Hydroxydihydromorphines
Hosztafi, Sandor,Berenyi, Sandor,Toth, Geza,Makleit, Sandor
, p. 435 - 442 (2007/10/02)
A new route for the stereohomogeneous synthesis of N-demethyl-N-substituted-14-hydroxydihydromorphines 2a-f has been elaborated, involving O-demethylation of the novel dihydrocodeine derivatives 6a-f, obtained upon alkylation of the hitherto unknown N-demethyl-14-hydroxydihydrocodeine (5). Keywords. 6α,14β-Diacetoxy-4,5α-epoxy-3-methoxy-17-methyl-morphinan, N-demethylation of; 3,6α,14β-Triacetoxy-17-alkyl-4,5α-epoxymorphinan, N-demethylation of; 17-Alkyl-4,5α-epoxy-6α,14β-dihydroxy-3-methoxymorphinan, O-demethylation of; 4,5α-Epoxy-6α,14β-dihydroxy-3-methoxymorphinan, N-alkylation of.
