20412-84-4Relevant academic research and scientific papers
Transition-Metal-Free Arylation of N -Alkyl-tetrahydroisoquinolines under Oxidative Conditions: A Convenient Synthesis of C1-Arylated Tetrahydro-isoquinoline Alkaloids
Singh, Kamal Nain,Kessar, Satinder V.,Singh, Paramjit,Singh, Pushpinder,Kaur, Manjot,Batra, Aanchal
supporting information, p. 2644 - 2650 (2015/12/26)
A simple protocol for the C1 arylation of tetrahydroisoquinolines with aryl Grignard reagents via diethyl azodicarboxylate (DEAD) mediated oxidative C-H activation under metal-free conditions has been developed. The target compounds, including some natura
Preparation of N-benzylsulfonamido-1,2-dihydroisoquinolines and their reaction with Raney nickel. A mild, new synthesis of isoquinolines
Larghi, Enrique L.,Kaufman, Teodoro S.
, p. 3159 - 3162 (2007/10/03)
N-benzylsulfonamido-1,2-dihydroisoquinolines react with Raney nickel to provide isoquinotines in excellent yields and under mild, neutral conditions.
