204136-24-3Relevant articles and documents
α-substituted malonester amides: Tools to define the relationship between ACAT inhibition and adrenal toxicity
Sliskovic, Drago R.,Picard, Joseph A.,O'Brien, Patrick M.,Liao, Peggy,Howard Roark,Roth, Bruce D.,Anderson, Maureen A.,Mueller, Sandra Bak,Bocan, Thomas M.A.,Bousley, Richard F.,Hamelehle, Katherine L.,Homan, Reynold,Reindel, James F.,Stanfield, Richard L.,Turluck, Daniel,Krause, Brian R.
, p. 682 - 690 (2007/10/03)
We prepared a series of α-substituted malonester amides that were evaluated for their ability to inhibit acyl-CoA:cholesterol O-acyl transferase activity in vitro and to lower plasma total cholesterol levels in a variety of cholesterol-fed animal models.
