20416-09-5

Basic information

• Product Name: 5-(PHENYLMETHYL)-3-FURANMETHANOL
• Synonyms: 5-(phenylmethyl)-3-furanmethano;2-BENZIL-4-HYDROXYMETHYLFURAN;5-(PHENYLMETHYL)-3-FURANMETHANOL;RESMETHRIN ALCOHOL METABOLITE;5-benzyl-3-furylmethanol;5-Benzyl-3-(hydroxymethyl)furan;5-Benzyl-3-furanmethanol;Resmethrin alcohol metabolite, 10 μg /μL in cyclohexane
• CAS NO: 20416-09-5
• Molecular Formula: C₁₂H₁₂O₂
• Molecular Weight: 188.22
• EINECS: 243-802-8
• Mol File: 20416-09-5.mol
• Article Data: 5

Chemical Properties

• Melting Point: 36-39 °C
• Boiling Point: 210.081 °C at 760 mmHg
• Flash Point: 80.854 °C
• Appearance: /
• Density: 1.138 g/cm³
• Vapor Pressure: 0.117mmHg at 25°C
• Refractive Index: 1.57
• PKA: 14.21±0.10(Predicted)
• CAS DataBase Reference: 5-(PHENYLMETHYL)-3-FURANMETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(PHENYLMETHYL)-3-FURANMETHANOL(20416-09-5)
• EPA Substance Registry System: 5-(PHENYLMETHYL)-3-FURANMETHANOL(20416-09-5)

Safety Data

• Hazardous Substances Data: 20416-09-5(Hazardous Substances Data)

Usage

General Description

5-(Phenylmethyl)-3-furanmethanol is a chemical compound with the molecular formula C12H12O2. It is a colorless to pale yellow liquid with a faint, sweet, floral odor. 5-(PHENYLMETHYL)-3-FURANMETHANOL is used as a flavoring agent in the food and beverage industry, as well as in the production of perfumes and other fragrances. It is also used in the synthesis of pharmaceuticals and other organic compounds. 5-(Phenylmethyl)-3-furanmethanol is considered to be relatively low in toxicity, but it should be handled with care and proper safety precautions.

InChI:InChI=1/C12H12O2/c13-8-11-7-12(14-9-11)6-10-4-2-1-3-5-10/h1-5,7,9,13H,6,8H2

Upstream product

• 158360-01-1 4-(hydroxymethyl)-2-furancarboxaldehyde 
• 100-44-7 benzyl chloride 
• 20416-08-4 methyl 5-benzylfuran-3-carboxylate 
• 1569083-76-6 (E)-methyl 2-(acetoxymethyl)-5-phenylpent-2-en-4-ynoate 
• 1569083-78-8 (E)-methyl 2-(hydroxymethyl)-5-phenylpent-2-en-4-ynoate 

Downstream Products

• 49550-78-9 [5-(phenylmethyl)-3-furanyl]methyl cis-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate 
• 109430-44-6 5-benzyl-furan-3-ylmethyl endo-tricyclo[5.2.1.02,6 ]decane-2-exo-carboxylate 
• 10453-86-8 resmethrin 
• 151059-59-5 (1R-trans)-3-<<<<4-<<2-(trimethylsilyl)ethoxy>carbonyl>cyclohexyl>methyl>amino>carbonyl>-2,2-dimethylcyclopropane-1-carboxylic acid, <2-(phenylmethyl)-4-furyl>methyl ester 
• 151059-60-8 trans-4-<<<<(1R-trans)-3-<<<2-(phenylmethyl)-4-furyl>methoxy>carbonyl>-2,2-dimethyl-1-cyclopropyl>carbonyl>amino>methyl>cyclohexane-1-carboxylic acid 
• 151059-56-2 (1R-trans)-4-<<<3-<<<2-(phenylmethyl)-4-furyl>methoxy>carbonyl>-2,2-dimethyl-1-cyclopropyl>carbonyl>oxy>butanoic acid 
• 151059-55-1 (1R-trans)-2,2-dimethylcyclopropane-1,3-dicarboxylic acid, <2-(phenylmethyl)-4-furyl>methyl monoester 
• 34878-15-4 5-benzyl-furan-3-carbaldehyde 
• 109430-44-6 5-benzylfur-3-ylmethyl endo-tricyclo<5.2.1.0^2,6>decane-exo-2-carboxylate 

Relevant articles and documents

A 2-benzyl-furan-4-methanol synthesis method

The invention discloses a method for synthesizing 2-benzyl furan-4-methanol. The method comprises the following steps: (1) reacting a hydroxyl protecting agent with 4-hydroxymethyl furan-2-formaldehyde, so as to obtain a compound of which the structure is shown in a formula a; (2) mixing a phenyl carbon anion reagent with a compound of which the structure is shown in the formula a, and reacting to obtain a compound of which the structure is shown in a formula b; (3) removing a hydroxyl protection groups from the compound of which the structure is shown in the formula b, and then carrying out hydrogenolysis, thereby obtaining the 2-benzyl furan-4-methanol.

Isoxazolines as intermediates to furans

Isoxazolines of the general formula II STR1 in which R1, R2, R3 and R4 are each unsubstituted or halogen-, haloalkyl-, alkoxy-, haloalkoxy-, nitro-, cyano-, dialkylphosphonyl- or alkoxycarbonyl-substituted alkyl, aryl, aralkyl, alkoxycarbonyl or dialkoxyphosphonyl, R2 and R4 are each also hydrogen and R3 is also hydroxyalkyl which is unblocked or blocked by a detachable protective group or is haloalkyl, X is hydrogen or a detachable protective group, are used to prepare furans.

Pentafluorobenzyl esters

The (+), (-) and (±) forms of the compounds of the general formula (I) STR1 characterized in that R1 is a halo group; or a lower alkyl, lower alkoxy or lower alkylthio group, each of which may be substituted with one or more halo groups; R2 is hydrogen or a methyl group; or R1 and R2 together form a methylenedioxy, or a difluoromethylenedioxy group or, with the carbon atoms to which they are attached, an aromatic or heteroaromatic ring; and A is one of the groups X or Y STR2 wherein X1 and X2 are the same or different and each is hydrogen or a fluoro, chloro, bromo or methyl group, with the proviso that if X1 is a fluoro group, then X2 should not be a bromo group; and X3 and X4 are the same or different and each is hydrogen or a fluoro group; and Y1, Y2, Y3, Y4, Y5 and Y6 are the same or different groups and each is hydrogen or a fluoro, bromo, chloro, or methyl group. The compounds (I) are insecticidally active.