204194-33-2

Upstream product

• 204194-31-0 3,4-bis(5-Fluoro-1H-indol-3-yl)-N-[4-(t-butyl)benzyl]-pyrrole-2,5-dione 

Downstream Products

• 406722-15-4 C₃₇H₃₂F₃N₃O₆ 
• 849824-62-0 3,9-difluoro-6-(4-tert-butylbenzyl)-12,13-dihydro-12-(2,3,6-tri-O-benzoyl-β-D-galactopyranosyl)indolo[2,3-a]-pyrrolo[3,4-c]carbazole-5,7-dione 

Relevant academic research and scientific papers

Practical synthesis of the rebeccamycin aglycone and related analogs by oxidative cyclization of bisindolylmaleimides with a Wacker-type catalytic system

Using atmospheric O2 as the stoichiometric oxidant, Pd2+/Cu2+-catalyzed oxidative cyclization of the corresponding bisindolylmaleimides provides the rebeccamycin aglycone and related indolo[2,3-a]pyrrolo[3,4-c]carbazoles in 58-88% yield. The method is operationally simple and utilizes readily prepared substrates, making the process amenable to scaleup.