2042-08-2

Basic information

• Product Name: 2-bromocholestan-3-one
• CAS NO: 2042-08-2
• Molecular Formula: C₂₇H₄₅BrO
• Molecular Weight: 465.5496
• Mol File: 2042-08-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 499.6°C at 760 mmHg
• Density: 1.108g/cm³
• Vapor Pressure: 4.09E-10mmHg at 25°C
• Refractive Index: 1.515
• CAS DataBase Reference: 2-bromocholestan-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromocholestan-3-one(2042-08-2)
• EPA Substance Registry System: 2-bromocholestan-3-one(2042-08-2)

Safety Data

• Hazardous Substances Data: 2042-08-2(Hazardous Substances Data)

Upstream product

• 1255-89-6 3-Acetoxy-5α-Δ²-Cholesten 
• 1255-89-6 5α-cholest-2-en-3-ol 3-acetate 
• 1753-61-3 2α,3α-epoxy-5α-cholestane 
• 566-88-1 dihydrocholesterone 
• 3903-53-5 2β-bromo-5α-cholestan-3β-ol 
• 1858-03-3 2β-bromo-3α-hydroxy-5-α-cholestane 

Downstream Products

• 104921-08-6 Cholestano-2'-phenyl<2,3-d>triazole 
• 106145-78-2 3α-phenylthio-2β-trifluoroacetoxy-<3β-(2)H>-5α-cholestane 
• 106145-76-0 2β-acetamido-3a-phenylthio<3-(2)H>-5α-cholestane 
• 106145-77-1 2β-hydroxy-3α-phenylthio-<3β-(2)H>-5α-cholestane 
• 13944-42-8 Cholestanone-2,3-dione bisphenylhydrazone 

Relevant articles and documents

STEREOCHIMIE-LVII ETUDE STEREOCHIMIQUE ET CINETIQUE DE LA BROMATION D'ESTERS ET D'ETHERS ENOLIQUES STEROIDIQUES

Absolute rates of bromination were measured for two series of derivatives of steroidal ketones 3, enol acetates 1 and enol methyl ether 2.Axial substituents exhibited a large effect on rates, which increased by 15,000 fold on going from (X=CH3; Y=CN) to (X=Y=H).From the bromide ion effect it was concluded that the first step (formation of an intermediate bromonium ion) was reversible and that the second step (formation of haloketones 4 or 5 or of haloacetals 8 or 9) was slow compared to the first step.The intermediate was concluded to be a highly unsymmetrical bromonium ion rather than a plain oxocarbenium ion.