204253-45-2Relevant academic research and scientific papers
Solid-phase synthesis of peptidomimetic oligomers with a phosphodiesterase backbone
Lin, Peishan,Ganesan
, p. 511 - 514 (2007/10/03)
An unnatural biopolymer is described in which amino acid side-chains are presented along a negatively charged phosphodiester backbone. For this purpose, a series of phosphoramidite monomers was prepared from chiral 1,2-diols. These were efficiently converted into oligomers using standard coupling conditions on an automated DNA synthesizer.
