204253-76-9Relevant articles and documents
New Synthesis of Fused Pyrimidine Derivatives via ortho-(Isocyanomethyl)nitroaromatic Compounds
Ostrowski, Stanislaw
, p. 180 - 187 (2007/10/03)
An efficient synthesis of functionalized fused pyrimidine derivatives from the respective ortho-(isocyanomethyl)nitroarenes is described.Hydrolysis of the isocyano group in the title isonitriles followed by catalytic reduction of the nitro group and subsequent cyclocondensation of the diamine formed with orthoesters leads to the final products.