20434-34-8

Basic information

• Product Name: 1-Butylcyclobutanol
• Synonyms: 1-Butylcyclobutanol
• CAS NO: 20434-34-8
• Molecular Formula: C8H16O
• Molecular Weight: 128.21
• Mol File: 20434-34-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 175 °C(Press: 751 Torr)
• Appearance: /
• Density: 0.8721 g/cm3
• PKA: 15.38±0.20(Predicted)
• CAS DataBase Reference: 1-Butylcyclobutanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Butylcyclobutanol(20434-34-8)
• EPA Substance Registry System: 1-Butylcyclobutanol(20434-34-8)

Safety Data

• Hazardous Substances Data: 20434-34-8(Hazardous Substances Data)

Upstream product

• 109-72-8 n-butyllithium 
• 1191-95-3 cyclobutanone 
• 693-04-9 butyl magnesium bromide 
• 693-03-8 n-butyl magnesium bromide 
• 2969-81-5 Ethyl 4-bromobutyrate 
• 20434-23-5 1-Brom-octanon-⁽⁴⁾ 

Relevant articles and documents

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Photoinduced Fragmentation Borylation of Cyclic Alcohols and Hemiacetals

A visible-light photoinduced fragmentation borylation of O-phthalimido cycloalkanols with bis(catecholato)diboron is described. Structurally diverse keto and formyloxy alkyl boronic esters are shown to be conveniently prepared by radical-mediated ring opening of cyclic alcohols and hemiacetals, respectively. The reactions proceed under mild conditions in the absence of additives or photocatalysts, display excellent functional group tolerance, and are shown to allow cleavage of 4-, 5-, 6-, and 7-membered ring substrates. The mechanism proceeds via sequential homolytic N-O and C-C bond cleavages, the latter of which involves β-scission of an alkoxy radical, generating a carbonyl and an alkyl radical that is trapped by the diboron reagent. Spectroscopic studies suggest direct photoexcitation of either the phthalimide or diboron substrates with blue light can initiate a radical chain mechanism.

Manganese-Catalyzed Electrochemical Deconstructive Chlorination of Cycloalkanols via Alkoxy Radicals

A manganese-catalyzed electrochemical deconstructive chlorination of cycloalkanols has been developed. This electrochemical method provides access to alkoxy radicals from alcohols and exhibits a broad substrate scope, with various cyclopropanols and cyclobutanols converted into synthetically useful β- and γ-chlorinated ketones (40 examples). Furthermore, the combination of recirculating flow electrochemistry and continuous inline purification was employed to access products on a gram scale.