204375-66-6

Usage

Physical state

Yellow-to-brown liquid at room temperature

Uses

Production of flavoring agents and fragrances, potential intermediate in chemical synthesis (pharmaceuticals and other organic compounds)

Hazards

Potential health and environmental risks, should be handled with caution

Upstream product

• 60-29-7 diethyl ether 
• 1540-34-7 3-ethyl-2,4-pentanedione 

Relevant academic research and scientific papers

Carbocations as Lewis acid catalysts: Reactivity and scope

One class of potential Lewis acids that has received negligible attention as a catalyst is the carbocation. Here we show the potential of triarylmethylium ions as highly powerful Lewis acid catalysts for organic reactions. The Lewis acidity of the triarylmethylium ion can be easily tuned by variation of the electronic properties of the aromatic rings and the catalytic activity of the carbocation is shown to correlate directly to the level of stabilization of the empty pC-orbital at the cationic carbon. The versatility of triarylmethylium ions as efficient Lewis acid catalysts for organic reactions is demonstrated in Diels-Alder, aza-Diels-Alder, conjugate addition, halogenation, epoxide rearrangement and intramolecular hetro-ene reactions.