204378-56-3

Upstream product

• 64145-56-8 (+/-)-7,7-dimethoxynorbornen-2-one 
• 61305-35-9 (R)-4-((tert-butyldimethylsilyl)oxy)cyclopent-2-enone 
• 824-94-2 p-methoxybenzyl chloride 
• 188910-40-9 ((S)-3-Bromo-cyclopent-3-enyloxy)-tert-butyl-dimethyl-silane 
• 188910-78-3 (3aR,5S,5aS,7S,8aR,8bS)-7-(tert-Butyl-dimethyl-silanyloxy)-5-hydroxy-4,5,5a,6,7,8,8a,8b-octahydro-3aH-as-indacen-3-one 
• 188910-60-3 (3aR,5S,5aS,7S,8aS,8bS)-7-(tert-Butyl-dimethyl-silanyloxy)-5-methoxymethoxy-decahydro-as-indacen-3-one 
• 188910-80-7 2-[(3aR,5S,5aS,7S,8aS,8bS)-7-(tert-Butyl-dimethyl-silanyloxy)-5-methoxymethoxy-1,3a,4,5,5a,6,7,8,8a,8b-decahydro-as-indacen-3-yl]-ethanol 
• 188910-56-7 (3aR,5S,5aS,7S,8aR,8bS)-7-(tert-Butyl-dimethyl-silanyloxy)-5-methoxymethoxy-4,5,5a,6,7,8,8a,8b-octahydro-3aH-as-indacen-3-one 
• 188910-52-3 (2S,3aS,5aR,8aS,8bR)-2-(tert-Butyl-dimethyl-silanyloxy)-6,6-dimethoxy-2,3,3a,5,5a,6,8a,8b-octahydro-1H-as-indacen-4-one 
• 204378-53-0 (5S,5aS,7S,8aR)-7-(tert-Butyl-dimethyl-silanyloxy)-5-methoxymethoxy-1,4,5,5a,6,7,8,8a-octahydro-2H-as-indacen-3-one 
• 188910-62-5 [(3aR,5S,5aS,7S,8aS,8bS)-7-(tert-Butyl-dimethyl-silanyloxy)-5-methoxymethoxy-1,3a,4,5,5a,6,7,8,8a,8b-decahydro-as-indacen-3-yl]-acetic acid methyl ester 
• 188910-79-4 [(3aR,5S,5aS,7S,8aS,8bS)-7-(tert-Butyl-dimethyl-silanyloxy)-5-methoxymethoxy-decahydro-as-indacen-(3Z)-ylidene]-acetic acid methyl ester 
• 204378-47-2 (-)-(S)-4-tert-butyldimethylsiloxy-1-cyclopenten-1-yl-trifluoromethanesulfonate 
• 188910-81-8 tert-Butyl-{(2S,3aS,4S,5aR,8aS,8bS)-6-[2-(4-methoxy-benzyloxy)-ethyl]-4-methoxymethoxy-1,2,3,3a,4,5,5a,8,8a,8b-decahydro-as-indacen-2-yloxy}-dimethyl-silane 

Downstream Products

• 188910-72-7 (2R,3aS,5aR,6R,7R,8aS,8bR)-7-(tert-Butyl-diphenyl-silanyloxy)-6-[2-(4-methoxy-benzyloxy)-ethyl]-1,2,3,3a,5a,6,7,8,8a,8b-decahydro-as-indacen-2-ol 
• 188910-85-2 2,2-Dimethyl-propionic acid (2R,3aS,5aR,6R,7R,8aS,8bR)-7-hydroxy-6-[2-(4-methoxy-benzyloxy)-ethyl]-1,2,3,3a,5a,6,7,8,8a,8b-decahydro-as-indacen-2-yl ester 
• 188910-86-3 2,2-Dimethyl-propionic acid (2R,3aS,5aR,6R,7R,8aS,8bR)-7-(tert-butyl-diphenyl-silanyloxy)-6-[2-(4-methoxy-benzyloxy)-ethyl]-1,2,3,3a,5a,6,7,8,8a,8b-decahydro-as-indacen-2-yl ester 
• 204381-17-9 2,2-Dimethyl-propionic acid (2R,3aS,5aR,6S,8aS,8bR)-6-[2-(4-methoxy-benzyloxy)-ethyl]-7-oxo-1,2,3,3a,5a,6,7,8,8a,8b-decahydro-as-indacen-2-yl ester 
• 188910-76-1 2,2-Dimethyl-propionic acid (2R,3aS,5aR,6R,8aS,8bR)-6-[2-(4-methoxy-benzyloxy)-ethyl]-7-oxo-1,2,3,3a,5a,6,7,8,8a,8b-decahydro-as-indacen-2-yl ester 

Relevant academic research and scientific papers

Total synthesis of spinosyn A. 1. Enantioselective construction of a key tricyclic intermediate by a multiple configurational inversion scheme

The condensation of (+)-7,7-dimethoxynorbomen-2-one with the cerium reagent derived from enantiopure bromide (+)-11 gives rise to an exo carbinol, which readily undergoes highly stereocontrolled anionic oxy-Cope rearrangement. Conversion of the resulting