2045-64-9

Usage

Chemical Structure

A derivative of 1,4-benzenediamine with a 2,4-dinitrophenyl group attached to the nitrogen atoms and two methyl groups attached to the nitrogen atoms as well.

Color

Yellow to orange

Industrial Applications

Production of dyes
Production of pigments
Production of polymers

Use as a Reagent

Commonly used in chemical synthesis

Detection of Amino Acids, Peptides, and Proteins

Used as a colorimetric reagent for the detection of these biomolecules

Hazardous Chemical

Considered a hazardous chemical and should be handled and stored with caution

Health and Environmental Risks

Potential risks if not handled and stored properly

Safety Precautions

Special care should be taken to prevent exposure and contamination during handling and storage.

Upstream product

• 977-41-3 2-nitro-benzenesulfonic acid-(2,4-dinitro-phenyl ester) 
• 99-98-9 4-amino-N,N-dimethylaniline 
• 70-34-8 2,4-Dinitrofluorobenzene 
• 97-00-7 1-chloro-2,4-dinitro-benzene 
• 120952-16-1 2-(2,4-dinitrophenoxy)-N-ethylpyridinium tetraphenylborate 

Downstream Products

• 158724-45-9 N¹-(4-dimethylamino-phenyl)-benzene-1,2,4-triyltriamine 
• 911137-90-1 1-(4-dimethylamino-phenyl)-2-methyl-1H-benzoimidazol-5-ylamine 

Relevant academic research and scientific papers

Novel benzimidazole-based MCH R1 antagonists

The identification of an MCH R1 antagonist screening hit led to the optimization of a class of benzimidazole-based MCH R1 antagonists. Structure-activity relationships and efforts to optimize pharmacokinetic properties are detailed along with the demonstration of the effectiveness of an MCH R1 antagonist in an animal model of obesity.

KINETICS OF THE REACTION OF 2-(2,4-DINITROPHENOXY)-N-ETHYLPYRIDINIUM TETRAPHENYLBORATE WITH AROMATIC AMINES IN ACETONITRILE

The reactions of 2-(2,4-dinitrophenoxy)-N-ethylpyridinium salts with arylamines take place by nucleophilic substitution at a carbon atom of the benzene ring with the formation of 2,4-dinitrodiphenylamine derivatives.The sensitivity coefficient (ρ0) to the induction effect of the substituents in the arylamine does not depend on the temperature in the range of 10-55 deg C and is equal to -6.89.The constant of the leaving group (τAr) for the 2-hydroxy-N-ethylpyridinium cation amounts to 1.66.