204512-95-8

Basic information

• Product Name: (S)-TETRAHYDROFURAN-3-AMINE HYDROCHLORIDE
• Synonyms: (S)-TETRAHYDROFURAN-3-AMINE HYDROCHLORIDE;(S)-3-aminotetrahydrofuran hydrochloride;(3S)-Tetrahydrofuran-3-aMine hydrochloride;(S)-3-AMinotetrahydrofuran, HCl;(3S)-oxolan-3-aMine hydrochloride;(3S)-Tetrahydro-3-furanaMine HCl;(S)-Tetrahydro-furan-3-ylamine hydrochloride;(S)-Tetrahydro-3-furylamine hydrochloride
• CAS NO: 204512-95-8
• Molecular Formula: C₄H₉NO*ClH
• Molecular Weight: 123.5813
• Mol File: 204512-95-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 173.5 °C at 760 mmHg
• Flash Point: 58.7 °C
• Appearance: /Solid
• Vapor Pressure: 1.09mmHg at 25°C
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: (S)-TETRAHYDROFURAN-3-AMINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-TETRAHYDROFURAN-3-AMINE HYDROCHLORIDE(204512-95-8)
• EPA Substance Registry System: (S)-TETRAHYDROFURAN-3-AMINE HYDROCHLORIDE(204512-95-8)

Safety Data

• Hazard Codes: Xn
• Statements: 22-37/38-41
• Safety Statements: 26-39
• Hazardous Substances Data: 204512-95-8(Hazardous Substances Data)

Usage

Uses

(S)-3-Aminotetrahydrofuran Hydrochloride is an intermediate used to prepare 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) Inhibitors.

InChI:InChI=1/C4H9NO.ClH/c5-4-1-2-6-3-4;/h4H,1-3,5H2;1H/t4-;/m0./s1

Upstream product

• 1070789-73-9 C₁₁H₁₅NO₃S 
• 152495-79-9 (S)-3-benzoylamino-tetrahydrofuran 

Downstream Products

• 104530-79-2 (S)-tetrahydrofuran-3-yl-amine 
• 1359969-64-4 2-(3-chloro-4-cyanophenyl)-3-cyclopentyl-N-((S)-tetrahydrofuran-3-yl)-3,3a,4,5-tetrahydro-2H-pyrazolo[3,4-f]quinoline-7-carboxamide 
• 1196509-67-7 C₃₂H₃₂F₂N₄O₆ 
• 1196509-58-6 3-(5-((1R,2S)-2-(2,2-difluoropropanamido)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)propoxy)-1H-indazol-1-yl)-N-((S)-tetrahydrofuran-3-yl)benzamide 
• 1073973-23-5 (S)-4-bromo-2-fluoro-6-((tetrahydrofuran-3-yl)amino)benzonitrile 
• 1572515-83-3 (S)-2-fluoro-5-(N-(tetrahydrofuran-3-yl)sulfamoyl)benzoic acid 
• 1572515-41-3 (S)-3-(N-(tetrahydrofuran-3-yl)sulfamoyl)benzoic acid 

Relevant articles and documents

Expeditious novel routes to enantiopure 3-amino tetrahydrofuran hydrochloride

The synthesis of chemically and enantiomerically pure (S)-3-amino tetrahydrofuran hydrochloride starting from the natural amino acids, l-aspartic acid or l-methionine is described. The process involves no chromatography and can be easily carried out on a large scale. The enantiopurity of the final product was established by NMR and chiral HPLC methods.

N6 mono heterocyclic substituted adenosine derivatives

A substituted N 6 -oxa, thia, thioxa and azacycloalkyl substituted adenosine derivative and a method for using the composition as an A 1 heart adenosine receptor.