204587-88-2

Basic information

• Product Name: Phosphonic acid, [2-oxo-2-[(4R)-2-oxo-4-(phenylmethyl)-3-oxazolidinyl]ethyl]-, diethyl ester
• CAS NO: 204587-88-2
• Molecular Formula: C16H22NO6P
• Molecular Weight: 355.328
• Mol File: 204587-88-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Phosphonic acid, [2-oxo-2-[(4R)-2-oxo-4-(phenylmethyl)-3-oxazolidinyl]ethyl]-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, [2-oxo-2-[(4R)-2-oxo-4-(phenylmethyl)-3-oxazolidinyl]ethyl]-, diethyl ester(204587-88-2)
• EPA Substance Registry System: Phosphonic acid, [2-oxo-2-[(4R)-2-oxo-4-(phenylmethyl)-3-oxazolidinyl]ethyl]-, diethyl ester(204587-88-2)

Safety Data

• Hazardous Substances Data: 204587-88-2(Hazardous Substances Data)

Upstream product

• 184714-56-5 (R)-4-benzyl-3-(2-chloroacetyl)oxazolidin-2-one 
• 122-52-1 triethyl phosphite 
• 40217-17-2 (R)-4-(phenylmethyl)-2-oxazolidinone 
• 110905-24-3 (4R)-3-(bromoacetyl)-4-(phenylmethyl)-2-oxazolidinone 

Downstream Products

• 550334-60-6 (R)-4-benzyl-3-((2E,8E,10E)-dodeca-2,8,10-trienoyl)-oxazolidin-2-one 
• 861899-30-1 (R)-3-((S,E)-7-(4-methoxybenzyloxy)-6-methylhept-2-enoyl)-4-benzyloxazolidin-2-one 
• 1312136-08-5 (R)-4-benzyl-3-((4R,6R,E)-7-(benzyloxy)-6-methyl-4-(tert-butyldimethylsilyloxy)hept-2-enoyl)oxazolidin-2-one 
• 184848-25-7 C₂₁H₃₁NO₃ 
• 1353545-65-9 C₂₁H₃₃NO₄Si 
• 1610030-01-7 C₂₇H₃₅NO₅ 

Relevant articles and documents

Conjugate addition of aryl nucleophiles to α,β-unsaturated cinnamic acid derivatives containing Evans type chiral auxiliaries

Cinnamides containing oxazolidin-2-one type auxiliaries have been prepared. A novel pathway to chiral 4-aryl-6-methyl-3,4-dihydrocoumrines via the asymmetric conjugate addition of arylmagnesium bromides to these cinnamides is described.

Identification of a nonbasic, nitrile-containing cathepsin K inhibitor (MK-1256) that is efficacious in a monkey model of osteoporosis

Herein, we report on the identification of nonbasic, potent, and highly selective, nitrile-containing cathepsin K (Cat K) inhibitors that are built on our previously identified cyclohexanecarboxamide core structure. Subsequent to our initial investigation

SELECTED CGRP ANTAGONISTS, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT

The invention relates to CGRP antagonists of general formula (I), in which A, U, V, W, X and R1 to R 3 are as defined in claim 1, the tautomers, diastereomers, enantiomers, hydrates, mixtures, salts, hydrates of the salts, in particular the physiologically-acceptable salts thereof with inorganic or organic acids, medicaments containing said compounds and the use and methods for production thereof.