204703-70-8

Basic information

• Product Name: Ethanone, 1-[2-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]-
• CAS NO: 204703-70-8
• Molecular Formula: C13H16O3
• Molecular Weight: 220.268
• Mol File: 204703-70-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-[2-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[2-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]-(204703-70-8)
• EPA Substance Registry System: Ethanone, 1-[2-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]-(204703-70-8)

Safety Data

• Hazardous Substances Data: 204703-70-8(Hazardous Substances Data)

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 118-93-4 o-hydroxyacetophenone 
• 142-68-7 TETRAHYDROPYRANE 

Downstream Products

• 888-12-0 (E)-2'-hydroxy-chalcone 
• 2875-23-2 (E)-3-(2-furanyl)-1-(2'-hydroxyphenyl)-2-propen-1-one 
• 13323-66-5 2',4-dihydroxychalcone 
• 2875-22-1 (E) -1-(2-hydroxyphenyl)-3-(thiophen-2-yl)prop-2-en-3-one 
• 845644-17-9 (E)-3-(3,4-dichlorophenyl)-1-(2'-hydroxyphenyl)prop-2-en-1-one 
• 118-93-4 o-hydroxyacetophenone 

Relevant articles and documents

Copper-catalyzed formation of C-O bonds by direct α-C-H bond activation of ethers using stoichiometric amounts of peroxide in batch and continuous-flow formats

Peroxides and ethers in flow: 2-Carbonyl-substituted phenols and β-ketoesters react safely with ethers in a microreactor environment using a copper catalyst and an organic peroxide (TBHP). This protocol results in unsymmetrical acetal scaffolds not easily available otherwise (see scheme). Copyright

Synthetic chalcones as potential anti-inflammatory and cancer chemopreventive agents

In an effort to develop potent anti-inflammatory and cancer chemopreventive agents, a series of chalcones were prepared by Claisen-Schmidt condensation of appropriate acetophenones with suitable aromatic aldehyde or prepared with appropriate dihydrochalco

Synthesis and description of chalcone-like compounds, inhibitors of aldose reductase

A series of hydroxy- and hydroxy-methoxychalcones was synthesized and the inhibitory activity and selectivity of the compounds towards bovine lens aldose reductase (AR) were tested. All the compounds display affinity for AR. The most active proved to be 1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)propen-1-one (isoliquiritigenin, IC50= 7.60 μM). The selectivity of this compound was also tested, its inhibitory activity being assayed against glutathione reductase and sorbitol dehydrogenase.