204840-48-2

Upstream product

• 204840-47-1 4-(1,1-diphenylmethoxy)benzyl alcohol 
• 558-13-4 carbon tetrabromide 

Downstream Products

• 1254062-04-8 7-(4-(benzhydryloxy)benzyloxy)-4-methyl-2H-chromen-2-one 
• 204839-22-5 4-amino-1-(4-(1,1-diphenylmethoxy)benzyl)pyridium bromide 

Relevant academic research and scientific papers

TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS

The invention relates to novel compounds for use in the treatment or prophylaxis of cancers and other proliferative conditions that are for example characterized by cells that express cytochrome P450 1B1 (CYP1B1) and allelic variants thereof. The invention also provides pharmaceutical compositions comprising one or more such compounds for use in medical therapy, for example in the treatment of prophylaxis of cancers or other proliferative conditions, as well as methods for treating cancers or other conditions in human or non-human animal patients. The invention also provides methods for identifying novel compounds for use in the treatment of prophylaxis of cancers and other proliferative conditions that are for example characterized by cells that express CYP1 B1 and allelic variants thereof. The invention also provides a method for determining the efficacy of a compound of the invention in treating cancer.

THROMBIN INHIBITORS

A compound which inhibits human thrombin and which has the general structure STR1