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20485-01-2

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20485-01-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 20485-01-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,4,8 and 5 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 20485-01:
(7*2)+(6*0)+(5*4)+(4*8)+(3*5)+(2*0)+(1*1)=82
82 % 10 = 2
So 20485-01-2 is a valid CAS Registry Number.

20485-01-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name Acetylaranotin

1.2 Other means of identification

Product number -
Other names LL-S-88-A

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:20485-01-2 SDS

20485-01-2Upstream product

20485-01-2Downstream Products

20485-01-2Relevant articles and documents

-

Nagarajan,R. et al.

, p. 2980 - 2982 (1968)

-

Total synthesis of (-)-Acetylaranotin

Fujiwara, Hideto,Kurogi, Taichi,Okaya, Shun,Okano, Kentaro,Tokuyama, Hidetoshi

, p. 13062 - 13065 (2013/02/26)

Epidithiodiketopiperazines are an important class of natural products because of their unique structural and biological properties. Among them, acetylaranotin (1), SCH64874 (2), compound 3, emethallicin A (4), MPC1001 (5), and emestrin (6) feature a dihydrooxepine moiety fused to a pyrrolidine/ epidithiodiketopiperazine (Figure 1). They also display a range of intriguing biological activities, such as: inhibitory activity against viral RNA polymerase, antagonistic activity of epidermal growth factor receptor, potent antituberculous activity, inhibitory activity against histamine release, antiproliferative activity against DU145 human prostate cancer cell line, and antagonistic activity of chemokine receptor (CCR2). While numerous synthetic approaches were investigated, only a limited number of successful preparations of the characteristic dihydrooxepine ring have been reported. During the synthetic studies on MPC1001, Peng and Clive established a synthetic method for a pyrrolidinone-fused dihydrooxepine through tetrahydrooxepine formation followed by selenoxide elimination.

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