2049-92-5Relevant academic research and scientific papers
Selective Acid-Catalyzed Hydroarylation of Nonactivated Alkenes with Aniline Assisted by Hexafluoroisopropanol
De Oliveira Vigier, Karine,Humblot, Anaelle,Jér?me, Fran?ois,Jiang, Fan,Peng, Gongming,Pera-Titus, Marc,Wischert, Raphael
, p. 17896 - 17905 (2021/12/13)
The catalytic hydroarylation of nonactivated alkenes with aniline is a reaction of high interest, aiming at providing C-functionalized aniline derivatives that are important precursors for the fabrication of polyurethanes. However, this reaction remains a
BENZIIMIDAZOLE AND IMIDAZOPYRIDINE DERIVATIVES AS SODIUM CHANNEL MODULATORS
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Page/Page column 179, (2013/08/15)
The invention relates to benzimidazole and imidazopyridine derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to new Nav1.8 modulators of formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7. X and Y are as defined in the description. Nav1.8 modulators are potentially useful in the treatment of a wide range of disorders, particularly pain.
Preparation of p-substituted, aromatic amines
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, (2008/06/13)
p-Substituted aromatic amines are prepared by reacting a p-substituted, aromatic carbamic acid ester with an aromatic amine in the presence of an aliphatic or cycloaliphatic alcohol. The aromatic amines obtainable by the process according to the invention are antiseptics and valuable starting materials for the preparation of dyes, resins, finishes, plastics, pesticides and drugs.
