204907-35-7Relevant academic research and scientific papers
4-Dimethylaminopyridine-catalyzed dynamic kinetic resolution in asymmetric synthesis of P-chirogenic 1,3,2-oxazaphospholidine-2-oxides
Wang, Lanlan,Cao, Shanshan,Du, Zhijun,Wu, Qiang,Bian, Zheng,Kang, Chuanqing,Gao, Lianxun,Zhang, Jingping
, p. 89665 - 89670 (2016)
Excellent diastereoselectivity (dr value up to 100: 0) was achieved in DMAP-catalyzed P-N bond formation in the synthesis of P-chirogenic organophosphines from phenylphosphonic dichloride (PhP(O)Cl2) and (S)-2-pyrrolidinemethanol derivatives. I
Chiral phosphinamides: New catalysts for the asymmetric reduction of ketones by borane
Burns, Barry,King, N. Paul,Tye, Heather,Studley, John R.,Gamble, Mark,Wills, Martin
, p. 1027 - 1038 (2007/10/03)
We have identified a new class of catalysts for the asymmetric reduction of prochiral ketones by borane. Key to the architecture of effective catalysts is an N-P=O structural unit which may be part of a phosphinamide, phosphonamide or a related structure.
New chiral phosphinamide catalysts for highly enantioselective reduction of ketones
Gamble, Mark P.,Studley, John R.,Wills, Martin
, p. 2853 - 2856 (2007/10/03)
A novel class of recoverable and highly stable phosphinamide catalysts for the asymmetric reduction of ketones by borane is described. Enantiomeric excesses of up to 92% have been obtained using 10 mol% of the optimum catalyst.
