204909-38-6 Usage
Description
AC-TBU-GLY-TBU-GLY-ASN(ME)2-ALA-AMC is a peptide chemical compound composed of a sequence of amino acids, including Tert-butyl glycine (TBU-GLY), N-methyl asparagine (ASN(ME)2), alanine (ALA), and amino-4-methylcoumarin (AMC). AC-TBU-GLY-TBU-GLY-ASN(ME)2-ALA-AMC is specifically designed for use in biochemical research, particularly as a fluorescent substrate for enzymatic assays and protease activity studies.
Uses
Used in Biochemical Research:
AC-TBU-GLY-TBU-GLY-ASN(ME)2-ALA-AMC is used as a fluorescent substrate for enzymatic assays and protease activity studies. The presence of the AMC group allows for the measurement of enzymatic activity through the detection of fluorescence when the peptide is cleaved by the protease. This makes it a valuable tool for studying enzyme kinetics and inhibitor screening.
Used in Enzyme Kinetics Studies:
In enzyme kinetics studies, AC-TBU-GLY-TBU-GLY-ASN(ME)2-ALA-AMC is used as a substrate to analyze the reaction rates and mechanisms of enzymatic reactions. The specific sequence of amino acids in the compound is designed for optimal substrate recognition and cleavage by certain proteases, providing insights into the enzyme's activity and specificity.
Used in Inhibitor Screening:
AC-TBU-GLY-TBU-GLY-ASN(ME)2-ALA-AMC is also used in inhibitor screening to identify potential enzyme inhibitors. By monitoring the fluorescence emitted upon peptide cleavage, researchers can assess the effectiveness of various compounds in inhibiting protease activity, which can be crucial for the development of new drugs and therapies.
Used in Pharmaceutical Development:
In the pharmaceutical industry, AC-TBU-GLY-TBU-GLY-ASN(ME)2-ALA-AMC can be employed as a tool for drug discovery and development. Its use in enzyme kinetics studies and inhibitor screening can help researchers understand the interactions between enzymes and potential drug candidates, ultimately leading to the design of more effective and targeted therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 204909-38-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,4,9,0 and 9 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 204909-38:
(8*2)+(7*0)+(6*4)+(5*9)+(4*0)+(3*9)+(2*3)+(1*8)=126
126 % 10 = 6
So 204909-38-6 is a valid CAS Registry Number.