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α-Methyl-DL-histidine dihydrochloride is a chemical compound with the molecular formula C7H11N3O2·2HCl. It is a derivative of histidine, an essential amino acid, where one of the hydrogen atoms on the α-carbon is replaced by a methyl group. This modification can affect the chemical properties and biological activity of the molecule. The dihydrochloride salt form of α-methyl-DL-histidine is used to improve its solubility in aqueous solutions, which is important for various applications in research and pharmaceuticals. It is often employed in studies related to histidine metabolism, enzyme inhibition, and as a potential therapeutic agent in certain conditions. The compound is also used as a research tool to investigate the mechanisms of action of histidine decarboxylase, an enzyme involved in histamine production.

20500-12-3

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20500-12-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 20500-12-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,5,0 and 0 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 20500-12:
(7*2)+(6*0)+(5*5)+(4*0)+(3*0)+(2*1)+(1*2)=43
43 % 10 = 3
So 20500-12-3 is a valid CAS Registry Number.

20500-12-3Downstream Products

20500-12-3Relevant academic research and scientific papers

SYNTHESIS OF α-METHYLHISTIDINE BY CATALYTIC PHASE-TRANSFER ALKYLATIONS

O'Donnell, Martin J.,Rusterholz, David B.

, p. 1157 - 1166 (2007/10/02)

α-Methylhistidine was prepared by two complementary routes using a catalytic phase-transfer alkylation procedure.Construction of the product was achieved either by alkylation of an alanine Schiff base ester with an imidazole-containing electrophile or by

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