205050-86-8

Basic information

• Product Name: 8-O-(tert-butyldimethylsilyl)-2-methyl-3-benzoyl-A-ring-pyrrole-duocarmycin B₂
• Synonyms: 8-O-(tert-butyldimethylsilyl)-2-methyl-3-benzoyl-A-ring-pyrrole-duocarmycin B₂
• CAS NO: 205050-86-8
• Molecular Weight: 732.746
• Mol File: 205050-86-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 8-O-(tert-butyldimethylsilyl)-2-methyl-3-benzoyl-A-ring-pyrrole-duocarmycin B₂(CAS DataBase Reference)
• NIST Chemistry Reference: 8-O-(tert-butyldimethylsilyl)-2-methyl-3-benzoyl-A-ring-pyrrole-duocarmycin B₂(205050-86-8)
• EPA Substance Registry System: 8-O-(tert-butyldimethylsilyl)-2-methyl-3-benzoyl-A-ring-pyrrole-duocarmycin B₂(205050-86-8)

Safety Data

• Hazardous Substances Data: 205050-86-8(Hazardous Substances Data)

Upstream product

• 246034-77-5 8-O-(tert-butyldimethylsilyl)-2-methyl-3-(benzyloxycarbonyl)-A-ring-pyrrole-duocarmycin B₂ 
• 246034-76-4 8-bromomethyl-4-(tert-butyl-dimethyl-silanyloxy)-1-hydroxy-2-methyl-6-(5,6,7-trimethoxy-1H-indole-2-carbonyl)-1,2,3,6,7,8-hexahydro-3,6-diaza-as-indacene-2-carboxylic acid allyl ester 
• 246034-75-3 8-bromomethyl-4-(tert-butyl-dimethyl-silanyloxy)-2-methyl-1-oxo-6-(5,6,7-trimethoxy-1H-indole-2-carbonyl)-1,2,3,6,7,8-hexahydro-3,6-diaza-as-indacene-2-carboxylic acid allyl ester 
• 205051-57-6 8-O-(tert-butyldimethylsilyl)-2-methyl-3-(allyloxycarbonyl)-A-ring-pyrrole-duocarmycin B₂ 
• 205051-58-7 8-O-(tert-butyldimethylsilyl)-2-methyl-3-carboxy-A-ring-pyrrole-duocarmicyn B₂ 
• 129953-15-7 8-O-tert-butyldimethylsilylduocarmycin B₂ 
• 93-97-0 benzoic acid anhydride 
• 183240-29-1 8-O-(tert-butyldimethylsilyl)-2-methyl-A-ring-pyrrole-duocarmyicin B₂ 

Relevant articles and documents

Synthesis and antitumor activity of duocarmycin derivatives: Modification of segment-A of A-ring pyrrole compounds

A series of 3-substituted A-ring pyrrole compounds of duocarmycin were synthesized and evaluated for in vitro anticellular activity against HeLa S3 cells and in vivo antitumor activity against murine sarcoma 180 in mice. These compounds were ev