205194-35-0

Basic information

• Product Name: 3-Piperidinemethanol,1-methyl-,(3S)-(9CI)
• Synonyms: 3-Piperidinemethanol,1-methyl-,(3S)-(9CI);(S)-1-Methyl-3-(hydroxymethyl)piperidine;[(S)-1-Methylpiperidin-3-yl]methanol;3-Piperidinemethanol, 1-methyl-, (3S)-;3-Piperidinemethanol,1-methyl-,(S)-;(3S)-1-methyl-3-Piperidinemethanol
• CAS NO: 205194-35-0
• Molecular Formula: C₇H₁₅NO
• Molecular Weight: 129.2
• Product Categories: AMINETERTIARY
• Mol File: 205194-35-0.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 142.5°C at 760 mmHg
• Flash Point: 94.4°C
• Appearance: /
• Density: 0.949g/cm³
• Vapor Pressure: 2.26mmHg at 25°C
• Refractive Index: 1.464
• PKA: 14.93±0.10(Predicted)
• CAS DataBase Reference: 3-Piperidinemethanol,1-methyl-,(3S)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Piperidinemethanol,1-methyl-,(3S)-(9CI)(205194-35-0)
• EPA Substance Registry System: 3-Piperidinemethanol,1-methyl-,(3S)-(9CI)(205194-35-0)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 205194-35-0(Hazardous Substances Data)

Usage

General Description

3-Piperidinemethanol,1-methyl, (3S)-(9CI) is a chemical compound with the molecular formula C7H15NO. It is a derivative of piperidine and belongs to the class of piperidines. The (3S) in its name indicates the stereochemistry of the compound. It is a colorless liquid with a boiling point of 182-184 °C. 3-Piperidinemethanol,1-methyl-,(3S)-(9CI) is used in organic synthesis and pharmaceutical research as a building block for the synthesis of various biologically active compounds. It may also have potential applications in the development of new drugs and agrochemicals. However, it is important to handle and use this compound with caution as it can be hazardous if not properly handled.

InChI:InChI=1/C7H15NO/c1-8-4-2-3-7(5-8)6-9/h7,9H,2-6H2,1H3/t7-/m0/s1

Upstream product

• 140695-84-7 tert-butyl (3S)-3-(hydroxymethyl)piperidine-1-carboxylate 
• 1346514-04-2 ethyl N-carbethoxy-piperidine-3S-carboxylate 

Downstream Products

• 1159598-45-4 [(3S)-1-methylpiperidin-3-yl]methyl 4-(4-methylphenyl)piperazine-1-carboxylate 
• 205193-44-8 (S)-4-(4-chloro-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-3-yl)methoxyquinazoline 

Relevant articles and documents

AMINOESTER DERIVATIVES

The invention relates to novel compounds which are both phosphodiesterase 4 (PDE4) enzymeinhibitorsand muscarinic M3 receptor antagonists, methods of preparing such compounds, compositions containing them and therapeutic use thereof.

Structural analysis of phenothiazine derivatives as allosteric inhibitors of the MALT1 paracaspase

Second site: In the crystal structure of human MALT1casp-Ig3 (mucosa-associated lymphoid tissue lymphoma translocation protein 1) in complex with the tricyclic phenothiazine derivative thioridazine (violet in the picture), the inhibitor is bound in a hydrophobic pocket far from the active site. This explains the action of phenothiazine derivatives as noncompetitive, reversible inhibitors. Copyright

METHODS OF USE FOR INHIBITORS OF AKT ACTIVITY

Invented is the use of 1 H-imidazo[4,5-c]pyridin-2-yl compounds in the treatment of specified cancers.