20529-22-0 Usage
Chemical Class
Piperazine derivatives
Usage
Intermediate in pharmaceutical synthesis, including clozapine
Therapeutic Properties
Antipsychotic and anxiolytic
Medical Application
Treatment of various psychiatric disorders
Mechanism of Action
Acts as a dopamine receptor antagonist and a serotonin receptor agonist
Neurotransmitter Modulation
Affects levels of neurotransmitters in the brain
Structural Components
Piperazine ring
Propylamine side chain
4-m-tolyl group
Pharmacological Effect
Determined by the presence of the 4-m-tolyl group
Potential
Useful building block in medicinal chemistry for psychiatric drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 20529-22-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,5,2 and 9 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 20529-22:
(7*2)+(6*0)+(5*5)+(4*2)+(3*9)+(2*2)+(1*2)=80
80 % 10 = 0
So 20529-22-0 is a valid CAS Registry Number.
20529-22-0Relevant academic research and scientific papers
Synthesis and biological evaluation of oxazole derivatives as T-type calcium channel blockers
Lee, Jie Eun,Koh, Hun Yeong,Seo, Seon Hee,Baek, Yi Yeon,Rhim, Hyewhon,Cho, Yong Seo,Choo, Hyunah,Pae, Ae Nim
scheme or table, p. 4219 - 4222 (2010/09/04)
T-type calcium channel is one of therapeutic targets for the treatment of cardiovascular diseases and neuropathic pain. In this study, as a part of our ongoing efforts to develop potent T-type calcium channel blockers, we designed oxazole derivatives subs
