205304-86-5 Usage
Uses
Used in Pharmaceutical Industry:
Tubulysin A, TubA is used as an antibiotic for its antimicrobial properties, helping to combat various bacterial infections.
Used in Anticancer Applications:
Tubulysin A, TubA is used as an anticancer agent for its ability to inhibit microtubule formation, induce apoptosis, and prevent cell proliferation. It is particularly effective against a wide range of cancers due to its multifaceted mode of action.
Used in Drug Delivery Systems:
Tubulysin A, TubA is used as a component in drug delivery systems to enhance the efficacy and targeted delivery of anticancer treatments. Its anti-angiogenic properties can also be utilized to disrupt the formation of new blood vessels that supply nutrients to tumors, further contributing to its potential as a therapeutic agent in cancer treatment.
Biochem/physiol Actions
Tubulysin A is a novel antibiotic, which is anti-microtubule, anti-mitotic, apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative. Tubulysins are cytotoxic peptides, which include 9 members (A-I). Tubulysin A has potential application as an anticancer agent. It arrests cells in the G2/M phase. Tubulysin A inhibits polymerization more efficiently than vinblastine and induces depolymerization of isolated microtubules. Tubulysin A has potent cytostatic effects on various tumor cell lines with IC50 in the picomolar range.
Check Digit Verification of cas no
The CAS Registry Mumber 205304-86-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,5,3,0 and 4 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 205304-86:
(8*2)+(7*0)+(6*5)+(5*3)+(4*0)+(3*4)+(2*8)+(1*6)=95
95 % 10 = 5
So 205304-86-5 is a valid CAS Registry Number.
