205319-10-4Relevant academic research and scientific papers
Palladium-Catalyzed Formal Insertion of Carbenoids into Aminals via C-N Bond Activation
Qin, Guiping,Li, Lixin,Li, Jiawen,Huang, Hanmin
supporting information, p. 12490 - 12493 (2015/10/19)
A new strategy for selective insertion of metal carbenes into C-N bond has been developed via Pd-catalyzed C-N bond activation. A series of aminals and α-diazoesters with different substituents were successfully incorporated even in 0.1 mol % of catalyst under mild conditions, affording a wide range of α,β-diamino acid esters with quarternary carbon-centers. Preliminary mechanistic studies uncovered that the unique electrophilic cyclopalladated species could easily react with diazoacetates to generate a Pd-carbenoid intermediate which was involved in the catalytic cycle.
Palladium complexes of P,P and P,S type bidentate ligands: Implication in Suzuki-Miyaura cross-coupling reaction
Saikia, Kokil,Deb, Biswajit,Borah, Bibek Jyoti,Sarmah, Podma Pollov,Dutta, Dipak Kumar
, p. 4293 - 4297 (2012/01/13)
New palladium complexes of the type [PdCl2(η2- P∩P)] (1a,1b) and [PdCl2(η2-P∩S)] (1c,1d) have been synthesised by the reaction of PdCl2 with P,P and P,S type bidentate ligands in 1:1 mol ratio, where,
The effect of the bite angle of diphosphane ligands on activity and selectivity in palladium-catalyzed cross-coupling
Kranenburg, Mirko,Kamer, Paul C. J.,Van Leeuwen, Piet W. N. M.
, p. 155 - 157 (2007/10/03)
The effect of the natural bite angle (βn) of diphosphane ligands on catalyst selectivity and activity in the palladiumcatalyzed cross-coupling of sec-butyl magnesium chloride with bromobenzene was investigated. The calculated natural bite angles range from 78° for dppe (1,2-bisdiphenylphosphanoethane) to 110° for Xantphos. The natural bite angle of diphosphane ligands has a large effect on catalyst selectivity and activity. Both rate and selectivity of the cross-coupling reaction increase with increasing bite angle and reach a maximum value with DPEphos (βn = 102.7° ). Larger bite angles of the diphosphane ligands result in a decreased selectivity and activity.
