205375-80-0

Upstream product

• 4559-70-0 Diphenylphosphine oxide 
• 205375-79-7 (R)-(-)-2,2'-bis(trifluoromethanesulfonyloxy)-5,5'-dichloro-4,4',6,6'-tetramethyl-1,1'-biphenyl 
• 88-04-0 4-Chloro-3,5-dimethylphenol 
• 188348-50-7 2,2'-dihydroxy-5,5'-dichloro-4,4',6,6'-tetramethyl-1,1'-biphenyl 
• 7688-25-7 1,4-di(diphenylphosphino)-butane 

Downstream Products

• 155566-50-0 (+/-)-3,3'-Dichloro-2,2',4,4'-tetramethyl-6-diphenylphosphino-6'-hydroxybiphenyl 

Relevant academic research and scientific papers

Synthesis of New Chiral Phosphinephosphites Having 2-Diphenylphosphinobiphenyl-2'-yl Backbone and Their Use in Rh(I)-Catalyzed Asymmetric Hydroformylations

New chiral phosphinephosphites (R)-(5,5'-dichloro-2-diphenylphosphino-4,4',6,6'-tetramethylbiphenyl-2'-yl)(S)-1,1'-binaphthalen-2,2'-diyl)phosphite and its enantiomer (S,R)-BIPHEMPHOS have been synthesized from 5,5'-dichloro-4,4',6,6'-tetramethyl-2,2'-biphenyldiol in enantiomerically pure form.Their Rh(I) complexes have been shown to be highly efficient catalysts for asymmetric hydroformylations of a variety of olefinic substrates.The corresponding phosphinephosphites derived from 2,2'-biphenyldiol were also tested as ligands for asymmetric hydroformylation.

Optically active diphosphine compound, method for making the compound, transition metal complex having the compound as ligand and method for making optically active substance by use of the complex

The present invention provides a ligand for a novel catalyst superior in such characteristics as selectivity (chemoselectivity and enantioselectivity) and catalytic activity in asymmetric synthesis reactions and a ligand for a novel catalyst effective in