205382-53-2

Basic information

• Product Name: (4aR,7S,8S,8aS)-8-(6-Amino-purin-9-yl)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol
• Synonyms: (4aR,7S,8S,8aS)-8-(6-Amino-purin-9-yl)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol
• CAS NO: 205382-53-2
• Molecular Weight: 369.38
• Mol File: 205382-53-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (4aR,7S,8S,8aS)-8-(6-Amino-purin-9-yl)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (4aR,7S,8S,8aS)-8-(6-Amino-purin-9-yl)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol(205382-53-2)
• EPA Substance Registry System: (4aR,7S,8S,8aS)-8-(6-Amino-purin-9-yl)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol(205382-53-2)

Safety Data

• Hazardous Substances Data: 205382-53-2(Hazardous Substances Data)

Upstream product

• 66224-66-6 adenine 
• 215441-82-0 Methanesulfonic acid (4aR,7S,8S,8aR)-7-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yl ester 
• 215441-79-5 Methanesulfonic acid (4aR,7S,8S,8aR)-8-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl ester 
• 89872-96-8 1,5-anhydro-4,6-O-benzylidene-2-O-tert-butyldimethylsilyl-D-glucitol 
• 89872-97-9 (4aR,7S,8R,8aR)-8-(tert-Butyl-dimethyl-silanyloxy)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol 
• 40428-86-2 sodium adeninate 

Downstream Products

• 215441-91-1 Dithiocarbonic acid O-[(4aR,7S,8S,8aS)-8-(6-amino-purin-9-yl)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl] ester S-methyl ester 
• 205382-61-2 9-((4aR,8S,8aS)-2-Phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yl)-9H-purin-6-ylamine 

Relevant articles and documents

Synthesis of 1,5-anhydro-D-mannitol nucleosides with a purine base moiety

D-Mannitol nucleosides with a purine base moiety have been conveniently synthesized strating from 1,5-anhydro-4,6-O-benzylidene-D-glucitol. The 3-OH function of 1,5-anhydro-4,6-O-benzylidene-D-glucitol was selectively protected with t-butyldimethylsilyl group and subsequently converted to the corresponding O-triflate derivative for the introduction of the nucleobase moietes. These nucleoside derivatives were transformed to 1,5-Anhydro-6-O- MMTr-2-(N6-benzoyladenin-9-yl)-2-deoxy-3-O-TBDMS-D-mannitol and 1,5-Anhydro- 6-O-MMTr-2-(N2-isobutyrylguanin-9-yl)-2-deoxy-3-O-TBDMS-D-mannitol, useful as the building blocks for oligonucleotide synthesis. Also, the synthesis of the corresponding fully deprotected anhydrohexitol nucleosides were achieved for evaluation of antiviral activity test.