205433-80-3Relevant articles and documents
Oxazolyl-aryloxyacetic acid derivatives and their use as ppar agonists
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, (2008/06/13)
Compounds represented by the following (I), and pharmaceutically acceptable salts, solvates and hydrates thereof, wherein R1 is an unsubstituted or substituted aryl, heteroaryl, cycloalkyl, aryl-alkyl, heteroaryl-alkyl or cycloalkyl-alkyl, R2 is H, alkyl or haloalkyl, the polymethylene chain (II), is saturated or may contain a carbon-carbon double bond, while n is 2, 3, 4, W is O or S, Y is an unsubsituted or substituted phenylene, naphthylene or 1, 2, 3, 4 tetrahydronaphthylene, R3 is H, alkyl or haloalkyl. R4 is H, alkyl, haloalkyl or a substituted or unsubstituted benzyl, are useful for modulating a peroxisome proliferator activated receptor, particularly in the treatment of diabetes mellitus.
Photochemistry of Substituted 4,4-Dimethoxy-2,5-Cyclohexadienones
Hong, Fang-Tsao,Lee, Kung-Shing,Tsai, Yow-Fu,Liao, Chun-Chen
, p. 1 - 12 (2007/10/03)
4,4-Dimethoxy-2,5-cyclohexadienones 9-14 were prepared from the corresponding hydroquinone monomethyl ethers by oxidation with thallium trinitrate in methanol. Irradiation of solutions of 9-13 in methanol with a broad band of UV light centered at 350 nm in a Rayonet reactor afforded 2-cyclopentenone derivatives 15-19 in moderate to excellent yields, whereas irradiation of 14 in methanol gave phenol 8 along with other unidentified products. Irradiation of 11-14 in benzene yielded substituted phenols. The plausible reaction pathways for the product formation are discussed.