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1-N-Boc-2-(hydroxymethyl)piperazine is a chemical compound characterized by the molecular formula C10H20N2O3. It is a derivative of piperazine, featuring a Boc (tert-butoxycarbonyl) group that acts as a protective agent for the amine functionality of the piperazine ring. This allows for selective functionalization of other parts of the molecule. The presence of a hydroxymethyl group further enhances its reactivity and potential for modification, making it a versatile compound in organic synthesis and pharmaceutical applications.

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  • 205434-75-9 Structure
  • Basic information

    1. Product Name: 1-N-Boc-2-(hydroxymethyl)piperazine
    2. Synonyms: 1-Boc-2-Hydroxymethyl-piperazine;1-N-Boc-2-(hydroxymethyl)piperazine;tert-Butyl 2-(hydroxyMethyl)piperazine-1-carboxylate;1-Boc-2-HydroxyMethyl-piperazin;1-Piperazinecarboxylic acid, 2-(hydroxymethyl)-, 1,1-dimethylethyl ester
    3. CAS NO:205434-75-9
    4. Molecular Formula: C10H20N2O3
    5. Molecular Weight: 216.2774
    6. EINECS: N/A
    7. Product Categories: Piperaizine
    8. Mol File: 205434-75-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 323.989 °C at 760 mmHg
    3. Flash Point: 149.743 °C
    4. Appearance: /
    5. Density: 1.085 g/cm3
    6. Vapor Pressure: 0mmHg at 25°C
    7. Refractive Index: 1.478
    8. Storage Temp.: 2-8°C(protect from light)
    9. Solubility: N/A
    10. PKA: 14.97±0.10(Predicted)
    11. CAS DataBase Reference: 1-N-Boc-2-(hydroxymethyl)piperazine(CAS DataBase Reference)
    12. NIST Chemistry Reference: 1-N-Boc-2-(hydroxymethyl)piperazine(205434-75-9)
    13. EPA Substance Registry System: 1-N-Boc-2-(hydroxymethyl)piperazine(205434-75-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 205434-75-9(Hazardous Substances Data)

205434-75-9 Usage

Uses

Used in Organic Synthesis:
1-N-Boc-2-(hydroxymethyl)piperazine is used as a reagent for the protection of amines in organic synthesis. The Boc group shields the amine, enabling selective reactions to occur at other sites within the molecule, which is crucial for the synthesis of complex organic compounds.
Used in Pharmaceutical Industry:
1-N-Boc-2-(hydroxymethyl)piperazine is utilized as a building block in the production of various drugs. Its ability to protect amines and provide additional reactivity through the hydroxymethyl group makes it a valuable component in the synthesis of biologically active compounds, contributing to the development of new medications and therapeutic agents.

Check Digit Verification of cas no

The CAS Registry Mumber 205434-75-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,5,4,3 and 4 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 205434-75:
(8*2)+(7*0)+(6*5)+(5*4)+(4*3)+(3*4)+(2*7)+(1*5)=109
109 % 10 = 9
So 205434-75-9 is a valid CAS Registry Number.
InChI:InChI=1/C10H20N2O3/c1-10(2,3)15-9(14)12-5-4-11-6-8(12)7-13/h8,11,13H,4-7H2,1-3H3

205434-75-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl 2-(hydroxymethyl)piperazine-1-carboxylate

1.2 Other means of identification

Product number -
Other names 1-N-Boc-2-(hydroxymethyl)piperazine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:205434-75-9 SDS

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