205444-03-7Relevant academic research and scientific papers
The presence of substituents on the aryl moiety of the aryl phosphoramidate derivative of d4T enhances anti-HIV efficacy in cell culture: A structure-activity relationship
Siddiqui, Adam Q.,Ballatore, Carlo,McGuigan, Christopher,De Clercq, Erik,Balzarini, Jan
, p. 393 - 399 (2007/10/03)
New substituted-aryl phosphoramidate derivatives of the anti-HIV drug d4T were synthesized as membrane-soluble intracellular prodrugs for the free bioactive phosphate to establish relationship(s) between compound structure and in vitro antiviral activity.
