2055013-64-2

Basic information

• Product Name: NH-(m-PEG8)2
• Synonyms: NH-(m-PEG8)2;NH-bis(m-PEG8)
• CAS NO: 2055013-64-2
• Molecular Formula: C34H71NO16
• Molecular Weight: 749.92464
• Mol File: 2055013-64-2.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 700.3±55.0 °C(Predicted)
• Appearance: /
• Density: 1.070±0.06 g/cm3(Predicted)
• Solubility: Soluble in Water, DMSO, DCM, DMF
• PKA: 8.39±0.19(Predicted)
• CAS DataBase Reference: NH-(m-PEG8)2(CAS DataBase Reference)
• NIST Chemistry Reference: NH-(m-PEG8)2(2055013-64-2)
• EPA Substance Registry System: NH-(m-PEG8)2(2055013-64-2)

Safety Data

• Hazardous Substances Data: 2055013-64-2(Hazardous Substances Data)

Usage

Description

NH-(m-PEG8)2 is a PEGylation reagent that features an amino (NH2) group, which allows it to react with carboxylic acids or activated NHS esters and carbonyls. This reagent is designed to facilitate the attachment of polyethylene glycol (PEG) chains to various molecules, enhancing their solubility, stability, and biocompatibility.

Uses

Used in Pharmaceutical Industry:
NH-(m-PEG8)2 is used as a PEGylation agent for improving the pharmacokinetic properties of drugs. By attaching PEG chains to drug molecules, it can increase their solubility, stability, and circulation time in the body, leading to enhanced therapeutic efficacy and reduced side effects.
Used in Bioconjugation:
NH-(m-PEG8)2 is used as a coupling agent for the formation of bioconjugates. Its reactive amino group allows for the attachment of PEG chains to biomolecules such as proteins, peptides, and nucleic acids, improving their stability, solubility, and bioavailability for various applications, including drug delivery, diagnostics, and therapeutics.
Used in Material Science:
NH-(m-PEG8)2 is used as a modifying agent for the functionalization of surfaces and materials. The PEGylation of surfaces can provide improved biocompatibility, reduced protein adsorption, and enhanced resistance to non-specific interactions, which is beneficial for applications in medical devices, sensors, and tissue engineering.