2055014-62-3

Basic information

• Product Name: Azido-PEG8-PFP ester
• Synonyms: Azido-PEG8-PFP ester
• CAS NO: 2055014-62-3
• Molecular Formula: C25H36F5N3O10
• Molecular Weight: 633.559456
• Mol File: 2055014-62-3.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Solubility: Soluble in DMSO, DCM, DMF
• CAS DataBase Reference: Azido-PEG8-PFP ester(CAS DataBase Reference)
• NIST Chemistry Reference: Azido-PEG8-PFP ester(2055014-62-3)
• EPA Substance Registry System: Azido-PEG8-PFP ester(2055014-62-3)

Safety Data

• Hazardous Substances Data: 2055014-62-3(Hazardous Substances Data)

Usage

Description

Azido-PEG8-PFP ester is a monodisperse PEG linker that features an azide and PFP ester moieties. The azide group is capable of engaging in Click Chemistry reactions with alkynes, DBCO, and BCN to form triazole groups, while the PFP ester is amine-reactive and exhibits greater resistance to hydrolysis than NHS esters.

Uses

Used in Bioconjugation Applications:
Azido-PEG8-PFP ester is used as a bioconjugation agent for the covalent attachment of biomolecules to other molecules or surfaces. Its amine reactivity and hydrolysis resistance make it a reliable choice for creating stable conjugates in various research and therapeutic applications.
Used in Drug Delivery Systems:
In the pharmaceutical industry, Azido-PEG8-PFP ester is used as a component in drug delivery systems to enhance the solubility, stability, and targeted delivery of therapeutic agents. The ability to form stable triazole linkages through Click Chemistry allows for the precise and efficient attachment of drug molecules to carriers or nanoparticles.
Used in Diagnostic Imaging:
Azido-PEG8-PFP ester is utilized as a contrast agent or labeling molecule in diagnostic imaging. Its compatibility with Click Chemistry enables the attachment of imaging probes or markers to biomolecules, improving the visualization and detection of specific biological processes or structures within the body.
Used in Materials Science:
In the field of materials science, Azido-PEG8-PFP ester is employed as a building block for the development of functional polymers and materials. The versatility of the azide group in Click Chemistry allows for the creation of complex structures and materials with tailored properties for various applications, such as sensors, actuators, or responsive materials.