2055014-69-0

Basic information

• Product Name: Fluorescein-PEG6-Acid
• Synonyms: Fluorescein-PEG6-Acid
• CAS NO: 2055014-69-0
• Molecular Formula: C36H42N2O13S
• Molecular Weight: 742.78928
• Mol File: 2055014-69-0.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Solubility: Soluble in Water, DMSO, DMF, DCM
• CAS DataBase Reference: Fluorescein-PEG6-Acid(CAS DataBase Reference)
• NIST Chemistry Reference: Fluorescein-PEG6-Acid(2055014-69-0)
• EPA Substance Registry System: Fluorescein-PEG6-Acid(2055014-69-0)

Safety Data

• Hazardous Substances Data: 2055014-69-0(Hazardous Substances Data)

Usage

Description

Fluorescein-PEG6-Acid is a xanthene dye with excitation/emission maximum 494/517 nm and a free terminal carboxyl acid. It features a hydrophilic PEG spacer that enhances solubility in aqueous media and reduces steric hindrance during binding. The terminal carboxylic acid can react with primary amine groups in the presence of activators, such as EDC or HATU, to form a stable amide bond. This property makes it suitable for use as a quantum yield standard.

Uses

Used in Bioconjugation:
Fluorescein-PEG6-Acid is used as a bioconjugation agent for attaching biomolecules to other molecules or surfaces. The terminal carboxylic acid allows for stable amide bond formation with primary amine groups, facilitating the attachment process.
Used in Fluorescence Imaging:
Fluorescein-PEG6-Acid is used as a fluorescent probe in various fluorescence imaging applications. Its excitation/emission maxima at 494/517 nm make it suitable for visualizing and tracking molecules or structures within biological samples.
Used in Drug Delivery Systems:
Fluorescein-PEG6-Acid can be used in drug delivery systems to improve the solubility and bioavailability of therapeutic agents. The hydrophilic PEG spacer enhances the compound's solubility in aqueous media, while the terminal carboxylic acid allows for attachment to drug molecules or carriers.
Used in Analytical Chemistry:
Fluorescein-PEG6-Acid is used as a quantum yield standard in analytical chemistry. Its well-defined fluorescence properties make it a reliable reference for calibrating fluorescence measurements and ensuring accurate results.
Used in Research and Development:
Fluorescein-PEG6-Acid is used in research and development for various applications, including the study of molecular interactions, development of new fluorescent probes, and optimization of drug delivery systems. Its versatile properties make it a valuable tool for scientific investigation and innovation.