N-Me-N-(PEG4-acid)2 is a crosslinker containing two PEG4-acid groups. The two terminal carboxylic acid groups can react with primary amines in the presence of activators such as EDC and HATU to form stable amide bonds. The hydrophilic PEG linkers increase the water solubility of the compound, with enhanced water solubility properties as the PEG chain length increases.
2055014-77-0
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Basic information
- Product Name: N-Me-N-(PEG4-acid)2
- Synonyms: N-Me-N-(PEG4-acid)2;N-Me-N-bis(PEG4-acid) HCl salt
- CAS NO:2055014-77-0
- Molecular Formula: C23H45NO12
- Molecular Weight: 527.6029
- EINECS: N/A
- Product Categories: N/A
- Mol File: 2055014-77-0.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 637.4±55.0 °C(Predicted)
- Flash Point: N/A
- Appearance: /
- Density: 1.158±0.06 g/cm3(Predicted)
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- PKA: 3.97±0.10(Predicted)
- CAS DataBase Reference: N-Me-N-(PEG4-acid)2(CAS DataBase Reference)
- NIST Chemistry Reference: N-Me-N-(PEG4-acid)2(2055014-77-0)
- EPA Substance Registry System: N-Me-N-(PEG4-acid)2(2055014-77-0)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 2055014-77-0(Hazardous Substances Data)
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2055014-77-0 Usage
Uses
Used in Pharmaceutical Industry:N-Me-N-(PEG4-acid)2 is used as a crosslinking agent for the conjugation of therapeutic agents, such as drugs or proteins, to improve their stability, solubility, and pharmacokinetic properties. The hydrophilic PEG linkers enhance the water solubility of the conjugated compounds, facilitating their delivery and reducing the likelihood of aggregation or precipitation.
Used in Bioconjugation:
N-Me-N-(PEG4-acid)2 is used as a bioconjugation agent to attach functional groups, such as targeting ligands or imaging agents, to therapeutic agents or drug delivery systems. The stable amide bonds formed with primary amines ensure the attachment remains intact under physiological conditions, allowing for precise targeting and controlled release of the therapeutic agents.
Used in Hydrogel Formation:
N-Me-N-(PEG4-acid)2 is used as a hydrogel crosslinker to create hydrogels with tunable mechanical properties and degradation rates. The hydrophilic PEG linkers contribute to the hydrogel's swelling behavior and water content, making it suitable for various biomedical applications, such as drug delivery, tissue engineering, and wound healing.
Used in Diagnostic Imaging:
N-Me-N-(PEG4-acid)2 is used as a contrast agent in diagnostic imaging techniques, such as magnetic resonance imaging (MRI) or computed tomography (CT). The hydrophilic PEG linkers enhance the contrast agent's solubility and circulation time in the body, improving the imaging quality and diagnostic accuracy.
Used in Cosmetic Industry:
N-Me-N-(PEG4-acid)2 is used as a solubility enhancer for hydrophobic active ingredients in cosmetic formulations. The hydrophilic PEG linkers improve the solubility and dispersion of the active ingredients, ensuring their effective delivery to the skin and enhancing the overall performance of the cosmetic products.
Check Digit Verification of cas no
The CAS Registry Mumber 2055014-77-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 2,0,5,5,0,1 and 4 respectively; the second part has 2 digits, 7 and 7 respectively.Calculate Digit Verification of CAS Registry Number 2055014-77:
(9*2)+(8*0)+(7*5)+(6*5)+(5*0)+(4*1)+(3*4)+(2*7)+(1*7)=120
120 % 10 = 0
So 2055014-77-0 is a valid CAS Registry Number.
2055014-77-0Upstream product
2055014-77-0Downstream Products
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N-Me-N-(PEG4-acid)2
