Aminooxy-PEG8-methane HCl salt is a water-soluble polyethylene glycol (PEG) reagent that features an aminooxy group and a methane group. Aminooxy-PEG8-methane HCl salt is known for its reactivity and sensitivity, making it a valuable tool in bioconjugation processes. The aminooxy group within the molecule is capable of reacting with an aldehyde to form an oxime bond, and when a reductant is introduced, it can result in the formation of a hydroxylamine linkage. Due to its high reactivity, Aminooxy-PEG8-methane HCl salt should be used promptly, ideally within one week of its synthesis to ensure optimal performance.
2055024-52-5
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Basic information
- Product Name: Aminooxy-PEG8-methane
- Synonyms: Aminooxy-PEG8-methane;Aminooxy-PEG8-methane HCl salt
- CAS NO:2055024-52-5
- Molecular Formula: C17H37NO9
- Molecular Weight: 399.48
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: Aminooxy-PEG8-methane(CAS DataBase Reference)
- NIST Chemistry Reference: Aminooxy-PEG8-methane(2055024-52-5)
- EPA Substance Registry System: Aminooxy-PEG8-methane(2055024-52-5)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 2055024-52-5(Hazardous Substances Data)
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2055024-52-5 Usage
Uses
Used in Bioconjugation:Aminooxy-PEG8-methane HCl salt is used as a bioconjugation agent for the formation of oxime and hydroxylamine linkages. Its application is particularly relevant in the creation of stable and functional bioconjugates, which are essential in various research and therapeutic applications.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Aminooxy-PEG8-methane HCl salt is used as a key component in the development of drug conjugates. The ability to form stable linkages with aldehyde-containing drug molecules allows for the creation of prodrugs with improved pharmacokinetic properties, such as enhanced solubility, stability, and targeted delivery.
Used in Diagnostics:
Aminooxy-PEG8-methane HCl salt is employed as a diagnostic tool in the development of imaging agents. The formation of stable bioconjugates with imaging labels, such as fluorescent dyes or radionuclides, enables the visualization and tracking of biological processes in vivo, providing valuable insights into disease mechanisms and treatment efficacy.
Used in Research and Development:
In research and development, Aminooxy-PEG8-methane HCl salt is utilized as a versatile building block for the synthesis of novel bioconjugates. Its reactivity and compatibility with various biomolecules make it an attractive candidate for the development of new research tools and therapeutic agents.
Used in Material Science:
Aminooxy-PEG8-methane HCl salt is also used in material science for the development of biocompatible materials and surfaces. The formation of stable linkages with aldehyde-containing polymers or surfaces allows for the creation of materials with tailored properties, such as improved biocompatibility, reduced immunogenicity, and enhanced cell adhesion.
Check Digit Verification of cas no
The CAS Registry Mumber 2055024-52-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 2,0,5,5,0,2 and 4 respectively; the second part has 2 digits, 5 and 2 respectively.Calculate Digit Verification of CAS Registry Number 2055024-52:
(9*2)+(8*0)+(7*5)+(6*5)+(5*0)+(4*2)+(3*4)+(2*5)+(1*2)=115
115 % 10 = 5
So 2055024-52-5 is a valid CAS Registry Number.
2055024-52-5Upstream product
2055024-52-5Downstream Products
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Aminooxy-PEG8-methane
