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m-PEG3-S-PEG4-propargyl is a PEG (polyethylene glycol) linker that features a propargyl group. This unique structure allows it to participate in copper-catalyzed azide-alkyne click chemistry, enabling the formation of stable triazole linkages with azide-bearing compounds or biomolecules. The hydrophilic PEG spacer within the molecule enhances its solubility in aqueous media, making it a versatile tool for various applications.

2055040-85-0

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2055040-85-0 Usage

Uses

Used in Bioconjugation:
m-PEG3-S-PEG4-propargyl is used as a bioconjugation agent for the selective and efficient attachment of biomolecules, such as proteins, peptides, or nucleic acids. The propargyl group facilitates the formation of stable triazole linkages through click chemistry, allowing for precise and site-specific conjugation.
Used in Drug Delivery Systems:
In the pharmaceutical industry, m-PEG3-S-PEG4-propargyl is used as a component in drug delivery systems to improve the solubility, stability, and bioavailability of therapeutic agents. The PEG spacer can help reduce the immunogenicity and increase the circulation time of drug carriers, while the propargyl group enables the attachment of drug molecules or targeting ligands via click chemistry.
Used in Diagnostics:
m-PEG3-S-PEG4-propargyl is used as a diagnostic tool for the development of imaging agents and sensors. The propargyl group can be utilized to attach imaging labels or recognition elements to biomolecules, allowing for the detection and monitoring of biological processes at the molecular level.
Used in Material Science:
In the field of material science, m-PEG3-S-PEG4-propargyl is used as a building block for the synthesis of functional polymers and hydrogels. The PEG spacer and propargyl group can be incorporated into polymer networks to create materials with tailored properties, such as enhanced biocompatibility, tunable degradation rates, or specific binding capabilities.
Used in Anticancer Applications:
Although not explicitly mentioned in the provided materials, given the versatility of m-PEG3-S-PEG4-propargyl and its potential use in drug delivery and bioconjugation, it could also be employed in the development of targeted anticancer therapies. The propargyl group could be used to attach cytotoxic agents or targeting ligands to biomolecules, enabling selective delivery and enhanced efficacy against cancer cells.

Check Digit Verification of cas no

The CAS Registry Mumber 2055040-85-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 2,0,5,5,0,4 and 0 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2055040-85:
(9*2)+(8*0)+(7*5)+(6*5)+(5*0)+(4*4)+(3*0)+(2*8)+(1*5)=120
120 % 10 = 0
So 2055040-85-0 is a valid CAS Registry Number.

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