2055041-59-1

Basic information

• Product Name: NH-(PEG4-acid)2
• Synonyms: NH-(PEG4-acid)2;NH-bis(PEG4-acid) HCl salt
• CAS NO: 2055041-59-1
• Molecular Formula: C22H43NO12
• Molecular Weight: 513.58
• Mol File: 2055041-59-1.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 639.3±55.0 °C(Predicted)
• Appearance: /
• Density: 1.165±0.06 g/cm3(Predicted)
• PKA: 3.97±0.10(Predicted)
• CAS DataBase Reference: NH-(PEG4-acid)2(CAS DataBase Reference)
• NIST Chemistry Reference: NH-(PEG4-acid)2(2055041-59-1)
• EPA Substance Registry System: NH-(PEG4-acid)2(2055041-59-1)

Safety Data

• Hazardous Substances Data: 2055041-59-1(Hazardous Substances Data)

Usage

Description

NH-(PEG4-acid)2, also known as NH-bis(PEG4-acid) HCl salt, is a branched polyethylene glycol (PEG) compound that is reactive with activated NHS esters under neutral or slightly basic conditions. The terminal carboxylic acids of this molecule can react with primary amino groups in the presence of activators such as HATU or EDC, making it a versatile building block for the conjugation of various molecules.

Uses

Used in Bioconjugation:
NH-(PEG4-acid)2 is used as a linker for bioconjugation applications due to its ability to react with primary amino groups in the presence of activators. This allows for the attachment of different molecules, such as drugs, proteins, or other biological entities, to create conjugates with improved properties or functionalities.
Used in Drug Delivery Systems:
In the pharmaceutical industry, NH-(PEG4-acid)2 is used as a component in the development of drug delivery systems. Its reactive nature allows for the attachment of drug molecules to create prodrugs or drug conjugates with enhanced solubility, stability, and targeted delivery.
Used in Diagnostics:
NH-(PEG4-acid)2 can be utilized in the development of diagnostic tools, such as imaging agents or biosensors, by conjugating it with specific targeting moieties or signaling molecules to improve their performance and specificity.
Used in Material Science:
In the field of material science, NH-(PEG4-acid)2 can be employed as a building block for the synthesis of novel materials with tailored properties, such as hydrogels, micelles, or nanoparticles, for various applications, including drug delivery, tissue engineering, and environmental remediation.