2055045-04-8

Basic information

• Product Name: (+)-Biotin-PEG6-NHS Ester
• Synonyms: (+)-Biotin-PEG6-NHS Ester
• CAS NO: 2055045-04-8
• Molecular Formula: C29H48N4O12S
• Molecular Weight: 676.77602
• Mol File: 2055045-04-8.mol

Chemical Properties

• Appearance: /
• Density: 1.31±0.1 g/cm3(Predicted)
• PKA: 13.90±0.40(Predicted)
• CAS DataBase Reference: (+)-Biotin-PEG6-NHS Ester(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-Biotin-PEG6-NHS Ester(2055045-04-8)
• EPA Substance Registry System: (+)-Biotin-PEG6-NHS Ester(2055045-04-8)

Safety Data

• Hazardous Substances Data: 2055045-04-8(Hazardous Substances Data)

Usage

Uses

Used in Biochemical Research:
(+)-Biotin-PEG6-NHS Ester is used as a labeling agent for biomolecules, such as proteins and peptides, to facilitate their detection, purification, and immobilization. The biotinylation process allows for the attachment of biotin, which can be easily recognized by streptavidin or avidin, enabling various downstream applications.
Used in Drug Development:
(+)-Biotin-PEG6-NHS Ester is used as a biotinylation agent for the development of drug conjugates, particularly in the creation of antibody-drug conjugates (ADCs). The biotinylation of antibodies or other targeting molecules allows for the attachment of therapeutic payloads, enhancing the specificity and efficacy of the drug.
Used in Diagnostics:
(+)-Biotin-PEG6-NHS Ester is used as a component in the development of diagnostic assays, such as enzyme-linked immunosorbent assays (ELISA) and Western blotting. The biotinylated molecules can be detected using streptavidin-conjugated enzymes or fluorescent dyes, providing a sensitive and specific signal for the detection of target analytes.
Used in Cell Biology:
(+)-Biotin-PEG6-NHS Ester is used as a cell surface labeling agent for the identification and isolation of specific cell populations. The biotinylation of cell surface proteins allows for the selective enrichment of target cells, which can be further analyzed or sorted using magnetic or fluorescence-activated cell sorting (FACS) techniques.
Used in Drug Delivery Systems:
(+)-Biotin-PEG6-NHS Ester is used as a biotinylation agent for the development of targeted drug delivery systems. The biotinylated molecules can be selectively taken up by cells expressing specific receptors, such as avidin or streptavidin, improving the specificity and efficacy of the drug delivery.
Used in Analytical Chemistry:
(+)-Biotin-PEG6-NHS Ester is used as a derivatization agent for the enhancement of detection sensitivity in various analytical techniques, such as mass spectrometry and chromatography. The biotinylation of analytes can improve their detection and quantification, providing more accurate and reliable results.