205518-20-3

Upstream product

• 4291-69-4 2,3,4,6-Tetra-O-benzyl-D-glucopyranose 
• 176787-43-2 carbonic acid cyclohexylmethyl ester 4-nitro-phenyl ester 
• 100-51-6 benzyl alcohol 

Downstream Products

• 74709-50-5 cyclohexylmethyl 2,3,4,6-tetra-O-benzyl-β-D-glucopyranoside 
• 74741-49-4 cyclohexylmethyl 2,3,4,6-tetra-O-benzyl-α-D-glucopyranoside 
• 205518-24-7 Carbonic acid cyclohexylmethyl ester (3R,4S,5S,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl ester 

Relevant academic research and scientific papers

An α-selective glycosylation via decarboxylation of mixed carbonate catalyzed by the combination of lewis acid and silver perchlorate

A catalytic amount of SnCl4-AgClO4 or Cp2HfCl2-2AgClO4 promoted decarboxylation of the 1-O-carbonates of the sugars to afford the α-glycosides stereoselectively. In this glycosylation reaction, the carbonate acts a leaving group of the glycosyl donor and also a cap of hydroxyl group in the acceptor alcohol.

A novel intramolecular decarboxylative glycosylation via mixed carbonate

A two-step glycosylation procedure, which involves (1) linking two sugars by using carbonate as a connector, (2) removing carbon dioxide to form a glycosidic bond by the aid of Lewis acid, has been developed. This glycosylation procedure was based on the opposite mode of connection, where a glycosyl acceptor was activated to link sugars.