205654-37-1

Usage

Uses

As the provided materials do not specify any particular applications for (+/-)-trans-2-[3-methoxy-4-(4-chlorophenylthioethoxy)-5-(N-methyl-N-hydroxyureidyl)methylphenyl]-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran, it is not possible to list its uses based on the information given. However, given the compound's unique structure and functional groups, it may have potential applications in various fields such as pharmaceuticals, materials science, or as a chemical intermediate. Further research, analysis, and testing would be required to determine its specific properties and potential uses in different industries.

Upstream product

• 32315-10-9 bis(trichloromethyl) carbonate 
• 4229-44-1 N-methylhydroxyamine hydrochloride 
• 154544-30-6 1-(3-methoxy-4-hydroxyethoxy-5-iodophenyl)-4-(3,4,5-trimethoxyphenyl)-1,4-butanedione 
• 154544-29-3 4-(2-hydroxyethoxy)-3-iodo-5-methoxybenzaldehyde 
• 106-54-7 p-Chlorothiophenol 
• 5438-36-8 5-iodovaniline 
• 193739-32-1 (+/-)-trans-2-[3-methoxy-4-(4-chlorophenylthioethoxy)-5-cyanophenyl]-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran 
• 154544-31-7 1-(3-methoxy-4-hydroxyethoxy-5-iodophenyl)-4-(3,4,5-trimethoxyphenyl)-1,4-butanediol 

Relevant academic research and scientific papers

Synthesis of (±)-trans-2-[3-methoxy-4-(4 chlorophenylthioethoxy)-5-(N-methyl-N-hydroxyureidyl)methylphenyl]-5-(3,4, 5-trimethoxyphenyl)tetrahydrofuran

The synthesis of (± )-trans-2-[3-methoxy-4-(4-chlorophenylthioethoxy)-5-(N-methyl-N-hydroxyureidyl) methylphenyl]-5-(3,4,5-trimethoxyphenyl) tetrahydrofuran from commercially available vanillin acetate and 3,4,5-trimethoxy benzaldehyde is reported.

(+/-)-trans-2-[3-methoxy-4-(4-chlorophenylthioethoxy)-5-(N-methyl-N- hydroxyureidyl)methylphenyl]-5-(3,4, 5-trimethoxyphenyl)tetrahydrofuran (CMI-392), a potent dual 5-lipoxygenase inhibitor and platelet-activating factor receptor antagonist.

By incorporating an N-hydroxyurea functionality onto diaryltetrahydrofurans, a novel series of compounds was investigated as dual 5-lipoxygenese (5-LO) inhibitor and platelet-activating factor (PAF) receptor antagonist. These dual functional compounds wer