205676-18-2

Upstream product

• 13361-64-3 trimethyl(propargyl)silane 
• 91-78-1 1,3,5-triphenylhexahydro-1,3,5-triazine 
• 615-36-1 2-bromoaniline 
• 95-51-2 o-chloroaniline 
• 615-43-0 2-iodophenylamine 
• 118670-86-3 N-(but-3-en-1-yl)-2-iodoaniline 
• 88933-19-1 methoxymethylphenylamine 

Downstream Products

• 491-35-0 C₆H₄NCH₂CHCCH₂ 

Relevant academic research and scientific papers

Observations on the intramolecular Heck reactions of aromatic chlorides using palladium/imidazolium salts

The intramolecular Heck reaction of aromatic amines and ethers using palladium/imidazolium salts is described. The use of tetra-n-butylammonium halide salts facilitates the reactivity of aromatic chlorides. An unexpected and novel palladium-mediated cyclisation is also described leading to the formation of a tricyclic adduct.

Addition of propargyltrimethylsilane to N-methyleneamine equivalents: Generation and electrophilic cyclization of vinylic carbocations

Lewis acid induced N-methyleneamine equivalents from N-(methoxymethyl)anilines or 1,3,5-triphenylhexahydro-1,3,5-triazines reacted with propargyltrimethylsilanes to give N-buta-2,3-dienylanilines, 4-methylene-1,2,3,4-tetrahydroquinolines and its oxidized product of 4-methylquinolines. These products came from branching reactions of the elimination and electrophilic aromatic substitution from the same vinylic carbocation intermediate.