20571-15-7

Usage

Uses

Used in Organic Synthesis:
Spiro[2.3]hexan-4-one is used as a building block in organic synthesis for the production of various pharmaceuticals, agrochemicals, and other fine chemicals. Its unique spirocyclic structure and carbonyl group make it a valuable component in the synthesis of complex organic molecules.
Used in Flavor and Fragrance Industry:
In the flavor and fragrance industry, Spiro[2.3]hexan-4-one is used as a scent component in various products. Its distinct aroma profile contributes to the overall scent of perfumes, colognes, and other fragranced products.
Used in Medicinal Applications:
Spiro[2.3]hexan-4-one is of interest for potential medicinal uses due to its anti-inflammatory and anti-fungal properties. It may be employed as an active ingredient in pharmaceutical formulations targeting inflammation and fungal infections.

Upstream product

• 27567-82-4 bicyclopropylidene 
• 33509-32-9 1-bromo-4-chlorobicyclo<2.2.0>hexane 
• 52952-63-3 7-oxatrispiro<2.0.2.1>heptane 
• 73496-25-0 C₁₄H₁₃N₃O₂ 
• 39762-73-7 Sulfuryldioxy-1,1'-bicyclopropyl 
• 39546-97-9 Bis(trimethylsilyoxy)-1,1'-bicyclopropyl 
• 18914-34-6 1-methylenespiro[2.2]pentane 

Downstream Products

• 445306-48-9 5-amino-spiro[2.3]hexane-5-carboxylic acid ethyl ester 
• 21426-37-9 Dispiro <2.0.2.2.>octan 

Relevant academic research and scientific papers

Cyclopropyl building blocks in organic synthesis. Part 81: Striving for unusually strained oxiranes: Epoxidation of spirocyclopropanated methylenecyclopropanes

1-Oxa[3]triangulane 13, the epoxide of methylenespiropentane, is thermally stable up to 300°C, but immediately rearranges to spiro[2.3]hexan-4-one (7) in the presence of lithium iodide at ambient temperature. The permethylated bicyclopropylidene 10 is sim

Hepatitis C virus inhibitors

The present invention relates to tripeptide compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. In particular, the present invention provides novel tripeptide analogs, pharmaceutical compositions containing such analogs and methods for using these analogs in the treatment of HCV infection.

HETEROCYCLICSULFONAMIDE HEPATITIS C VIRUS INHIBITORS

The present invention relates to tripeptide compounds, compositionscontaining such compounds and methods for using such compounds for the treatment of heptitis C virus (HCV) infection. In particular, the present invention provides novel tripeptide analogs, pharmaceutical compositionscontaining such analogs and methods for using these analogs in the treatment of HCV infection.

Hepatitis C virus inhibitors

The present invention relates to tripeptide compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. In particular, the present invention provides novel tripeptide analogs, pharmaceutical compositions containing such analogs and methods for using these analogs in the treatment of HCV infection.

Strain energies in [n]triangulanes and spirocyclopropanated cyclobutanes: An experimental study

The enthalpies of formation for trispiro[2.0.0.2.1.1]nonane (3), [3]rotane (4), n-heptyl[3]rotane (6), spiro-[2.3]hexane (7), and the isomeric dispiro[2.0.2.2]octane (8) and dispiro[2.1.2.1]octane (9), as well as [4]rotane (10), have been determined by me

Bicyclopropylidene: Cycloadditions onto a Unique Olefin

Bicyclopropylidene (1) is capable of undergoing cycloadditions in at least six different modes, depending on the nature of the cycloaddend.In analogy to its cyclodimerization, 1 adds in a and fashion to 1,3-dienes, most probably via dira

BICYCLOHEX-1(4)-ENE

The preparation of bicyclohex-1(4)-ene (1) via ring expansion of a cyclopropylcarbene or the dehalogenation of 1-bromo-4-chlorobicyclohexane is described.It is one of the most reactive of the alkenes which may be observed at room temperature.Its reactions, including dimerization and cycloaddition reactions, are described.The latter lead to convenient preparations of propellanes.The vibrational spectrum was examined via matrix isolation and ab initio MO calculations.

The chemistry of small-ring compounds. Part 49. A route to oxaspiropentanes, undisturbed by rearrangement

The title compounds have been prepared in 70-90percent yield by epoxidation of appropriate cyclopropylidene compounds with KHSO5 in a phosphate buffer in the presence of acetone.The latter is converted into an unstable dioxirane, which acts as the oxygen-transferring agent.

PHOTOOXYGENATION OF BICYCLOPROPYLIDENE

Upon photooxidation bicyclopropylidene (1) yields spiro hexan-4-one (4) and 7-oxatrispiroheptane (6).The formation of these is rationalized.Authentic 6 was prepared by epoxidation of 1, and 4 by isomerization of 6.